NF-κB Pathway Antibody Sampler Kit - #KF2025

   规格 价格 库存
 1kit RMB¥ 5480 现货

货期: 现货

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产品描述

货号:
KF2025
来源:
Rabbit, Goat
应用:
WB, IHC, IF/ICC, IP, ELISA
反应:
Hm, Rt, Mk, Ms, Rb
产品包含:
货号 产品 规格 来源 应用 反应 文献引用
AF2006 P-NF-kB p65 (Ser536) Ab 20ul Rabbit WB,IHC,IF/ICC,IP Hm,Rt,Mk 293
AF5006 NF-kB p65 Ab 20ul Rabbit WB,IHC,IF/ICC Hm,Ms,Rt,Mk 311
AF6014 IKK alpha/ beta Ab 20ul Rabbit WB,IHC,IF/ICC Hm,Ms,Rt 14
AF3013 P-IKK alpha/ beta (Ser180/Ser181) Ab 20ul Rabbit WB,IHC,IF/ICC Hm,Ms,Rt 24
AF5002 IKB alpha Ab 20ul Rabbit WB,IHC,IF/ICC Hm,Ms,Rt 100
AF2002 P-IKB alpha (Ser32/Ser36) Ab 20ul Rabbit WB,IHC,IF/ICC Hm,Ms,Rt,Mk 120
AF7011 Tubulin beta Ab 20ul Rabbit WB,IHC,IF/ICC Hm,Ms,Rt 74
S0001 Goat Anti-Rabbit IgG HRP 100ul Goat WB,IHC,ELISA Rb 454
简介:
The NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) pathway is a central signaling pathway involved in regulating immune responses, inflammation, cell survival, and proliferation. In its inactive state, NF-κB dimers are sequestered in the cytoplasm by inhibitory proteins known as IκBs (inhibitor of κB). Upon activation by various stimuli, such as pro-inflammatory cytokines, microbial products, or cellular stress, the IκBs are phosphorylated and degraded, allowing NF-κB dimers to translocate into the nucleus. Once in the nucleus, NF-κB regulates the expression of target genes involved in immune and inflammatory responses, cell proliferation, and apoptosis. Dysregulation of the NF-κB pathway has been implicated in various diseases, including inflammatory disorders, autoimmune diseases, cancer, and neurodegenerative diseases.
储存条件:
Store at -20 °C. Stable for 12 months from date of receipt.

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