产品: Tubulin beta 抗体
货号: AF7011
描述: Rabbit polyclonal antibody to Tubulin beta
应用: WB IHC IF/ICC
文献验证: WB, IF/ICC
反应: Human, Mouse, Rat
蛋白号: P07437
RRID: AB_2827688

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   规格 价格 库存
 50ul RMB¥ 450 现货
 100ul RMB¥ 750 现货
 200ul RMB¥ 1000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-1:5000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
Tubulin beta Antibody detects endogenous levels of total Tubulin beta.
RRID:
AB_2827688
引用格式: Affinity Biosciences Cat# AF7011, RRID:AB_2827688.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

TUBB3, CDCBM, Beta III Tubulin, Class III beta-tubulin, TUBB4, Tubulin, beta 3, Tubulin beta-III, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin, beta 3 class III, CFEOM3A

抗原和靶标

免疫原:

A synthesized peptide derived from human Tubulin beta.

基因/基因ID:
描述:
TUBB3 Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.

研究领域

· Cellular Processes > Transport and catabolism > Phagosome.   (View pathway)

· Cellular Processes > Cellular community - eukaryotes > Gap junction.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Pathogenic Escherichia coli infection.

文献引用

1). Biomimetic Multichannel Silk Nerve Conduits With Multicellular Spatiotemporal Distributions for Spinal Cord Injury Repair. Advanced materials (Deerfield Beach, Fla.), 2024 (PubMed: 39268784) [IF=27.4]

2). Efficient Therapy of Inflammatory Bowel Disease (IBD) with Highly Specific and Durable Targeted Ta2C Modified with Chondroitin Sulfate (TACS). Advanced Materials, 2023 (PubMed: 37224059) [IF=27.4]

3). SOX9 Modulates the Transformation of Gastric Stem Cells Through Biased Symmetric Cell Division. Gastroenterology, 2023 (PubMed: 36740200) [IF=25.7]

4). The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers. Cell Host & Microbe, 2019 (PubMed: 31513772) [IF=20.6]

Application: WB    Species: human    Sample: HEK293 cells

Figure 3.| Oligomerized SAFA Mediates IFNb Transcription(I) HEK293 cells were transfected with indicated plasmids and infected with virus for 6 h, followed by oligomerization assay.

5). Passively-targeted mitochondrial tungsten-based nanodots for efficient acute kidney injury treatment. Bioactive materials, 2023 (PubMed: 36185743) [IF=18.9]

6). Heterozygous de novo dominant negative mutation of REXO2 results in interferonopathy. Nature communications, 2024 (PubMed: 39107301) [IF=16.6]

7). Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis. Nature communications, 2025 (PubMed: 39905002) [IF=16.6]

8). CircFndc3b Mediates Exercise-Induced Neuroprotection by Mitigating Microglial/Macrophage Pyroptosis via the ENO1/KLF2 Axis in Stroke Mice. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025 (PubMed: 39467260) [IF=15.1]

9). Opsonization Inveigles Macrophages Engulfing Carrier-Free Bilirubin/JPH203 Nanoparticles to Suppress Inflammation for Osteoarthritis Therapy. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024 (PubMed: 38593402) [IF=15.1]

10). Hierarchical Targeting Nanodrug with Holistic DNA Protection for Effective Treatment of Acute Kidney Injury. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025 (PubMed: 39703158) [IF=15.1]

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