产品: LY96 抗体
货号: DF6669
描述: Rabbit polyclonal antibody to LY96
应用: WB IHC
文献验证: IHC
反应: Human, Rat
预测: Horse, Dog
蛋白号: Q9Y6Y9
RRID: AB_2838631

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 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Rat
克隆:
Polyclonal
特异性:
LY96 Antibody detects endogenous levels of total LY96.
RRID:
AB_2838631
引用格式: Affinity Biosciences Cat# DF6669, RRID:AB_2838631.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ESOP 1; ESOP-1; ESOP1; LY 96; Ly-96; LY96; LY96_HUMAN; Lymphocyte antigen 96; md 2; MD 2 protein; MD2 protein; Myeloid differentiation protein 2; Protein MD 2; Protein MD-2; Protein MD2;

抗原和靶标

免疫原:

A synthesized peptide derived from human LY96, corresponding to a region within the internal amino acids.

基因/基因ID:
描述:
This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.

研究领域

· Environmental Information Processing > Signal transduction > NF-kappa B signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Pathogenic Escherichia coli infection.

· Human Diseases > Infectious diseases: Bacterial > Pertussis.

· Human Diseases > Infectious diseases: Parasitic > Toxoplasmosis.

· Organismal Systems > Immune system > Toll-like receptor signaling pathway.   (View pathway)

文献引用

1). Identification of Key Biomarkers Associated with Immunogenic Cell Death and Their Regulatory Mechanisms in Severe Acute Pancreatitis Based on WGCNA and Machine Learning. International journal of molecular sciences, 2023 (PubMed: 36769358) [IF=5.6]

Application: IHC    Species: human    Sample:

Figure 9. Clinical and animal experimental validation of ICD-related hub genes. (A) Relative mRNA expression of the three hub genes in SAP patients versus healthy controls; (B) Representative HE-stained micrographs of the pancreas and lungs (original magnification ×100 and ×200); (C–E) Serum expressional levels of α-amylase, IL-1β, TNF-α by ELISA. (F) Immunohistochemical plots showing hub genes in SAP rats and controls (original magnification ×100 and ×200); (F) Semiquantitative results of hub genes based on immunohistochemistry. (G) Immunohistochemical plots showing hub genes in SAP rats and controls (original magnification ×100 and ×200). Data are shown as mean ± SEM, ** p < 0.01, *** p < 0.001.

2). Patchouli alcohol ameliorates acute liver injury via inhibiting oxidative stress and gut-origin LPS leakage in rats. International Immunopharmacology, 2021 (PubMed: 34182243) [IF=4.8]

3). TLR3 as an emerging molecule facilitating pyroptosis in the context of rheumatoid arthritis: A study combined bioinformatics and experimental validation. Cytokine, 2025 (PubMed: 39884182) [IF=3.7]

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