PRKAA1 Antibody - #BF9215

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产品: PRKAA1 抗体
货号: BF9215
描述: Mouse monoclonal antibody to PRKAA1
应用: WB IHC IF/ICC ELISA FACS
反应: Human, Mouse, Rat, Monkey
蛋白号: Q13131
RRID: AB_2846224

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   规格 价格 库存
 50ul RMB¥ 1500 现货
 100ul RMB¥ 2500 现货

货期: 当天发货

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相关下载
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse
应用:
ELISA (, Elisa) 1:10000, FCM (Flow Cytometric) 1:200-1:400, IF/ICC (Immunofluorescence Analysis) 1:200-1:1000, IHC (Immunohistochemical Analysis) 1:200-1:1000, WB (Western Blotting) 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat, Monkey
克隆:
Monoclonal [AFB17816]
特异性:
PRKAA1 antibody detects endogenous levels of total PRKAA1.
RRID:
AB_2846224
引用格式: Affinity Biosciences Cat# BF9215, RRID:AB_2846224.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Ascitic fluid containing 0.03% sodium azide. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

5 AMP activated protein kinase alpha 1catalytic subunit;5 AMP activated protein kinase catalytic alpha 1 chain;5' AMP activated protein kinase catalytic subunit alpha 1;5'-AMP-activated protein kinase catalytic subunit alpha-1;AAPK1;AAPK1_HUMAN;ACACA kinase;acetyl CoA carboxylase kinase;AI194361;AI450832;AL024255;AMP -activate kinase alpha 1 subunit;AMP-activated protein kinase, catalytic, alpha -1;AMPK 1;AMPK alpha 1;AMPK alpha 1 chain;AMPK;AMPK subunit alpha-1;AMPK1;AMPKa1;AMPKalpha1;C130083N04Rik;cb116;EC 2.7.11.1;HMG CoA reductase kinase;HMGCR kinase;hormone sensitive lipase kinase;Hydroxymethylglutaryl CoA reductase kinase;im:7154392;kinase AMPK alpha1;MGC33776;MGC57364;OTTHUMP00000161795;OTTHUMP00000161796;PRKAA 1;PRKAA1;Protein kinase AMP activated alpha 1 catalytic subunit;SNF1-like protein AMPK;SNF1A;Tau protein kinase PRKAA1;wu:fa94c10 antibody;

抗原和靶标

免疫原:

Purified recombinant fragment of human PRKAA1 expressed in E. Coli.

基因/基因ID:
PRKAA1(5562)
描述:
The protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

研究领域

· Cellular Processes > Transport and catabolism > Autophagy - animal.   (View pathway)

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

· Environmental Information Processing > Signal transduction > FoxO signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > mTOR signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > AMPK signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Apelin signaling pathway.   (View pathway)

· Human Diseases > Endocrine and metabolic diseases > Insulin resistance.

· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).

· Human Diseases > Cardiovascular diseases > Hypertrophic cardiomyopathy (HCM).

· Organismal Systems > Aging > Longevity regulating pathway.   (View pathway)

· Organismal Systems > Aging > Longevity regulating pathway - multiple species.   (View pathway)

· Organismal Systems > Environmental adaptation > Circadian rhythm.   (View pathway)

· Organismal Systems > Endocrine system > Insulin signaling pathway.   (View pathway)

· Organismal Systems > Endocrine system > Adipocytokine signaling pathway.

· Organismal Systems > Endocrine system > Oxytocin signaling pathway.

· Organismal Systems > Endocrine system > Glucagon signaling pathway.

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