CXCL11 Antibody - #DF9917

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产品: CXCL11 抗体
货号: DF9917
描述: Rabbit polyclonal antibody to CXCL11
应用: WB IHC
文献验证: WB, IHC
反应: Human
预测: Pig, Bovine, Horse, Sheep, Rabbit
蛋白号: O14625
RRID: AB_2843111

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   规格 价格 库存
 50ul RMB¥ 1500 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
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说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
CXCL11 Antibody detects endogenous levels of total CXCL11.
RRID:
AB_2843111
引用格式: Affinity Biosciences Cat# DF9917, RRID:AB_2843111.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

b R1; b-R1; Beta-R1; betaR1; C-X-C motif chemokine 11; Chemokine (C-X-C motif) ligand 11; Chemokine C-X-C motif ligand 11; CXC11; CXCL11; CXL11_HUMAN; H174; I TAC; I-TAC; Interferon gamma inducible protein 9; Interferon gamma-inducible protein 9; Interferon inducible T cell alpha chemoattractant; Interferon-inducible T-cell a chemoattractant I-TAC; Interferon-inducible T-cell alpha chemoattractant; IP 9; IP-9; IP9; ITAC; MGC102770; SCYB11; SCYB9B; Small inducible cytokine B11; Small inducible cytokine subfamily B (Cys-X-Cys) member 11; Small inducible cytokine subfamily B (Cys-X-Cys) member 9B; Small inducible cytokine subfamily B, member 11; Small inducible cytokine subfamily B, member 9B; Small-inducible cytokine B11;

抗原和靶标

免疫原:

A synthesized peptide derived from human CXCL11, corresponding to a region within the internal amino acids.

基因/基因ID:
CXCL11(6373)

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

· Organismal Systems > Immune system > Toll-like receptor signaling pathway.   (View pathway)

文献引用

1). Integrated immuno-transcriptomic analysis of ovarian cancer identifies a four-chemokine-dominated subtype with antitumor immune-active phenotype and favorable prognosis. British journal of cancer, 2024 (PubMed: 39095528) [IF=6.4]
2). Analysis of therapeutic targets and prognostic biomarkers of CXC chemokines in cervical cancer microenvironment. Cancer cell international, 2021 (PubMed: 34321012) [IF=5.8]

Application: IHC    Species: human    Sample: cervical cancer tissue

Fig. 4 Representative immunohistochemical images of distinct CXC chemokines in cervical cancer tissues and adjacent cervical tissues (χ400). We can observe that CXCL9/10/11/13 was highly expressed in cervical cancer tissues compared to adjacent cervical tissues
3). Study on the relationship between CXCR3 and its ligands and tubal tuberculosis. LIFE SCIENCES, 2021 (PubMed: 33454369) [IF=5.2]

Application: IHC    Species: Human    Sample: tubal tuberculosis

Fig. 4. CXCR3, CXCL9, CXCL10 and CXCL11 IHC staining. A: High-risk pregnancy monitoring control group CXCR3 Immunohistochemistry (×200); B: Mild Tubal Tuberculosis Group CXCR3 Immunohistochemistry (×200); C: Severe Tubal Tuberculosis Group CXCR3 Immunohistochemistry (×200); D: High-risk pregnancy monitoring control group CXCL9 Immunohistochemistry (×200); E: Mild Tubal Tuberculosis Group CXCL9 Immunohistochemistry (×200); F: Severe Tubal Tuberculosis Group CXCL9 Immunohistochemistry (×200); G: High-risk pregnancy monitoring control group CXCL10 Immunohistochemistry (×200); H: Mild Tubal Tuberculosis Group CXCL10 Immunohistochemistry (×200); I: Severe Tubal Tuberculosis Group CXCL10 Immunohistochemistry (×200); J: High-risk pregnancy monitoring control group CXCL11 Immunohistochemistry (×200); K: Mild Tubal Tuberculosis Group CXCL11 Immunohistochemistry (×200); L: Severe Tubal Tuberculosis Group CXCL11 Immunohistochemistry (×200).
4). Upregulation of ITGB6 in primary palmar hyperhidrosis. Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2023 (PubMed: 37212774) [IF=2.1]

Application: WB    Species: Human    Sample:

Fig. 6. Regulatory effects of integrin β6 (ITGB6) on CXCL3, CXCL5, CXCL10, CXCL11, and WNT2 expression levels in sweat gland cells. Sweat gland cells extracted from patients with primary palmar hyperhidrosis were treated with blank control or transfected with overexpression negative control (OE NC) or ITGB6 OE. The CXCL3, CXCL5, CXCL10, CXCL11, and WNT2 (A) mRNA (ITGB6 OE compared to control, Tukey’s honest significant difference (HSD), p < 0.001, all), and (B,C) protein expression (ITGB6 OE compared to control, CXCL3, CXCL5, and CXCL11: Tukey’s HSD, all p < 0.001; CXCL10: Tukey’s HSD, p = 0.004; WNT2: Tukey’s HSD, p = 0.027). The data are presented as mean ± 95% confidence interval (95% CI)

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