MIP-1 alpha Antibody - #DF8572

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产品: MIP-1 alpha 抗体
货号: DF8572
描述: Rabbit polyclonal antibody to MIP-1 alpha
应用: WB IHC
文献验证: WB, IHC
反应: Human
预测: Bovine, Horse
蛋白号: P10147
RRID: AB_2841776

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
MIP-1 alpha Antibody detects endogenous levels of total MIP-1 alpha.
RRID:
AB_2841776
引用格式: Affinity Biosciences Cat# DF8572, RRID:AB_2841776.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C C motif chemokine 3; CCL 3; CCL3; CCL3_HUMAN; Chemokine C C motif ligand 3; G0/G1 switch regulatory protein 19 1; G0/G1 switch regulatory protein 19-1; G0S19 1; G0S19 1 protein; Heparin binding chemotaxis protein; L2G25B; LD78 alpha; LD78-alpha(4-69); LD78alpha; Macrophage inflammatory protein 1 alpha; Macrophage inflammatory protein 1-alpha; MIP 1 alpha; MIP 1A; MIP-1-alpha; MIP-1-alpha(4-69); MIP1A; PAT 464.1; SCYA 3; SCYA3; SIS alpha; SIS beta; SIS-beta; Small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1a); Small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein;

抗原和靶标

免疫原:

A synthesized peptide derived from human MIP-1 alpha, corresponding to a region within the internal amino acids.

基因/基因ID:
CCL3(6348)

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Salmonella infection.

· Human Diseases > Infectious diseases: Parasitic > Chagas disease (American trypanosomiasis).

· Human Diseases > Immune diseases > Rheumatoid arthritis.

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

· Organismal Systems > Immune system > Toll-like receptor signaling pathway.   (View pathway)

文献引用

1). Identification of gene signatures associated with ulcerative colitis and the association with immune infiltrates in colon cancer. Frontiers in immunology, 2023 (PubMed: 36742294) [IF=5.7]

Application: IHC    Species: human    Sample:

Figure 5 Expression of CCL3, MMP3, and TIMP1 in UC patients and induced enteritis cells. (A) The expression of CCL3. (B) The expression of MMP3. (C) The expression of TIMP1. (D) The protein expression levels of CCL3, MMP3 and TIMP1 in UC patients and healthy controls. (E) The inflammatory factors IL-8 and IL-1β secretion level after 1 ug LPS stimulated NCM460 cells for 0h, 12h and 24h. (F) The protein expression levels of CCL3, MMP3 and TIMP1 in NCM460 cells stimulated with LPS for 0h, 12h and 24h.

Application: WB    Species: human    Sample:

Figure 5 Expression of CCL3, MMP3, and TIMP1 in UC patients and induced enteritis cells. (A) The expression of CCL3. (B) The expression of MMP3. (C) The expression of TIMP1. (D) The protein expression levels of CCL3, MMP3 and TIMP1 in UC patients and healthy controls. (E) The inflammatory factors IL-8 and IL-1β secretion level after 1 ug LPS stimulated NCM460 cells for 0h, 12h and 24h. (F) The protein expression levels of CCL3, MMP3 and TIMP1 in NCM460 cells stimulated with LPS for 0h, 12h and 24h.
2). Isosteviol reduces the acute inflammatory response after burns by upregulating MMP9 in macrophages leading to M2 polarization. International Immunopharmacology, 2022 (PubMed: 35176589) [IF=4.8]
3). Ghrelin inhibits early brain injury due to subarachnoid hemorrhage via the Tim-3-mediated HMGB1/NF-κB pathway. JOURNAL OF CHEMICAL NEUROANATOMY, 2022 (PubMed: 35863561) [IF=2.7]
4). Identification and preliminary validation of differently expressed genes as candidate biomarkers associated with atherosclerosis. Gene, 2024 (PubMed: 38527674) [IF=2.6]

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