CKS2 Antibody - #AF0616

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产品: CKS2 抗体
货号: AF0616
描述: Rabbit polyclonal antibody to CKS2
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse
预测: Pig, Zebrafish, Bovine, Sheep, Dog, Chicken, Xenopus
蛋白号: P33552
RRID: AB_2834233

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
CKS2 Antibody detects endogenous levels of total CKS2.
RRID:
AB_2834233
引用格式: Affinity Biosciences Cat# AF0616, RRID:AB_2834233.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CDC28; CDC28 protein kinase 2; CDC28 protein kinase regulatory subunit 2; CKS 2; CKS-2; CKS1(S. cerevisiae Cdc28/Cdc2 kinase subunit) homolog 2; Cks2; CKS2_HUMAN; CKSHS2; Cyclin dependent kinases regulatory subunit 2; Cyclin-dependent kinases regulatory subunit 2;

抗原和靶标

免疫原:

A synthesized peptide derived from human CKS2, corresponding to a region within the internal amino acids.

基因/基因ID:
CKS2(1164)
描述:
CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein.

研究领域

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Small cell lung cancer.   (View pathway)

文献引用

1). CKS2 Silencing Affects Proliferation and Apoptosis in Multiple Myeloma through the PTEN/ AKT/mTOR Pathway. Journal of Cancer, 2025 (PubMed: 40092696) [IF=3.3]

Application: WB    Species: Mouse    Sample:

Figure 1. CKS2 is highly expressed in multiple myeloma. A and B: The mRNA expression of CKS2 in the GSE6477 and GSE47552 datasets; C: RT-qPCR was used to detect the relative expression of CKS2 mRNA in clinical bone marrow specimens. D and E: Kaplan-Meier (K-M) survival analysis in GSE24080 and GSE4204 datasets. F and G: Immunohistochemistry and Western blot were used to detect the CKS2 expression in specimens. IHC magnification: X200. Data are shown as mean ± SEM. **p
2). Cyclin-dependent kinase subunit2 (CKS2) promotes malignant phenotypes and epithelial-mesenchymal transition-like process in glioma by activating TGFβ/SMAD signaling. Cancer Medicine, 2023 (PubMed: 36284444) [IF=2.9]

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