产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0529, RRID:AB_2834191.
展开/折叠
A kinase (PRKA) anchor protein 3; A-kinase anchor protein 110 kDa; A-kinase anchor protein 3; AKAP 110; AKAP-3; AKAP110; Akap3; AKAP3_HUMAN; Cancer/testis antigen 82; CT82; Fibrous sheath protein of 95 kDa; Fibrousheathin 1; Fibrousheathin I; Fibrousheathin-1; FSP95; PRKA3; protein kinase A binding protein AKAP 110; Protein kinase A-anchoring protein 3; SOB 1; SOB1; Sperm oocyte binding protein 1; Sperm oocyte-binding protein;
抗原和靶标
- O75969 AKAP3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKMDTSTDPVRVLSWLRRDLEKSTAEFQDVRFKPGESFGGETSNSGDPHKGFSVDYYNTTTKGTPERLHFEMTHKEIPCQGPRAQLGNGSSVDEVSFYANRLTNLVIAMARKEINEKIDGSENKCVYQSLYMGNEPTPTKSLSKIASELVNETVSACSRNAAPDKAPGSGDRVSGSSQSPPNLKYKSTLKIKESTKERQGPDDKPPSKKSFFYKEVFESRNGDYAREGGRFFPRERKRFRGQERPDDFTASVSEGIMTYANSVVSDMMVSIMKTLKIQVKDTTIATILLKKVLLKHAKEVVSDLIDSFLRNLHSVTGTLMTDTQFVSAVKRTVFSHGSQKATDIMDAMLRKLYNVMFAKKVPEHVRKAQDKAESYSLISMKGMGDPKNRNVNFAMKSETKLREKMYSEPKSEEETCAKTLGEHIIKEGLTLWHKTQQKECKSLGFQHAAFEAPNTQRKPASDISFEYPEDIGNLSLPPYPPEKPENFMYDSDSWAEDLIVSALLLIQYHLAQGGRRDARSFVEAAGTTNFPANEPPVAPDESCLKSAPIVGDQEQAEKKDLRSVFFNFIRNLLSETIFKRDQSPEPKVPEQPVKEDRKLCERPLASSPPRLYEDDETPGALSGLTKMAVSQIDGHMSGQMVEHLMNSVMKLCVIIAKSCDASLAELGDDKSGDASRLTSAFPDSLYECLPAKGTGSAEAVLQNAYQAIHNEMRGTSGQPPEGCAAPTVIVSNHNLTDTVQNKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGCSVGEVLQSVLRYEKERQLNEAVGNVTPLQLLDWLMVNL
翻译修饰 - O75969 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T34 | Phosphorylation | Uniprot | |
| S35 | Phosphorylation | Uniprot | |
| T36 | Phosphorylation | Uniprot | |
| S43 | Phosphorylation | Uniprot | |
| T102 | Phosphorylation | Uniprot | |
| S205 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| Y214 | Phosphorylation | Uniprot | |
| K225 | Acetylation | Uniprot | |
| K237 | Acetylation | Uniprot | |
| S403 | Phosphorylation | Uniprot | |
| Y404 | Phosphorylation | Uniprot | |
| T428 | Phosphorylation | Uniprot | |
| K433 | Ubiquitination | Uniprot | |
| S440 | Phosphorylation | Uniprot | |
| S612 | Phosphorylation | Uniprot | |
| S635 | Phosphorylation | Uniprot | |
| S636 | Phosphorylation | Uniprot |
研究背景
May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.
Phosphorylated on tyrosine residues.
Cytoplasmic vesicle>Secretory vesicle>Acrosome.
Note: Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.
Testis specific; only expressed in spermatids.
Interacts with ROPN1 AND ROPN1L. Interacts with QRICH2.
RII-binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
Belongs to the AKAP110 family.
限制条款
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