产品: GPR81 抗体
货号: DF2766
描述: Rabbit polyclonal antibody to GPR81
应用: WB IHC
文献验证: IHC
反应: Human, Mouse, Rat
预测: Horse, Dog
蛋白号: Q9BXC0
RRID: AB_2839972

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
GPR81 Antibody detects endogenous levels of total GPR81.
RRID:
AB_2839972
引用格式: Affinity Biosciences Cat# DF2766, RRID:AB_2839972.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FKSG80; FKSG80 protein; G protein coupled receptor 104; G protein coupled receptor 81; G protein coupled receptor GPR81; G-protein coupled receptor 104; G-protein coupled receptor 81; GPR 104; GPR 81; GPR104; GPR81; GPR81_HUMAN; HCA1; HCAR1; hydroxy-carboxylic acid receptor 1; Hydroxycarboxylic acid receptor 1; LACR1; lactate receptor 1; Putative chemokine receptor; T cell activation G protein coupled receptor; TA GPCR;

抗原和靶标

免疫原:

A synthesized peptide derived from human GPR81, corresponding to a region within C-terminal amino acids.

基因/基因ID:
描述:
Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.

研究领域

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

文献引用

1). Lactate as a metabolite from probiotic Lactobacilli mitigates ethanol-induced gastric mucosal injury: an in vivo study. BMC Complementary and Alternative Medicine, 2021 (PubMed: 33430871) [IF=3.3]

Application: IHC    Species: mice    Sample: gastric tissues

Fig. 6 Expression of lactate receptor GPR81 in the various groups (n = 4 per group). a Total RNA in gastric tissues was extracted and qPCR was carried out to examine the expression of genes encoding GPR81. C: Control group; D: disease group; L: Group treated with lactate at a dose of 3 g/ kg. The data were expressed as the means ± SD (n = 6). ** p < 0.01. b IHC staining for GPR81. Gastric samples were fixed and sectioned for staining by the primary antibody of GPR81. Brown granules in cells were considered as positive results

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