产品: | MAPRE2 抗体 |
货号: | DF2576 |
描述: | Rabbit polyclonal antibody to MAPRE2 |
应用: | WB |
反应: | Human, Mouse, Rat |
预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
分子量: | 37 kDa; 37kD(Calculated). |
蛋白号: | Q15555 |
RRID: | AB_2839782 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2576, RRID:AB_2839782.
展开/折叠
APC binding protein EB1; APC binding protein EB2; APC-binding protein EB2; EB1; EB2; End binding protein 2; End-binding protein 2; H.sapiens mRNA for novel T cell activation protein; MAPRE2; MARE2_HUMAN; Microtubule associated protein RP/EB family member 2; Microtubule-associated protein RP/EB family member 2; RP1; T cell activation protein EB1 family;
抗原和靶标
Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.
- Q15555 MARE2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPGPTQTLSPNGENNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).
Cytoplasm>Cytoskeleton.
Note: Associated with the microtubule network. Accumulates at the plus end of microtubules.
Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.
Interacts with DCTN1. Interacts with APC (via C-terminal). Interacts with monomeric and polymerized tubulin. Interacts with SLAIN1.
Composed of two functionally independent domains. The N-terminal domain forms a hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.
Belongs to the MAPRE family.
限制条款
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