产品: FGFP1 抗体
货号: DF2498
描述: Rabbit polyclonal antibody to FGFP1
应用: WB IHC
文献验证: WB
反应: Human
预测: Bovine
蛋白号: Q14512
RRID: AB_2839704

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
FGFP1 Antibody detects endogenous levels of total FGFP1.
RRID:
AB_2839704
引用格式: Affinity Biosciences Cat# DF2498, RRID:AB_2839704.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

17 kDa HBGF-binding protein; 17 kDa heparin binding growth factor binding protein; 17 kDa heparin-binding growth factor-binding protein; FGF binding protein 1; FGF BP; FGF BP1; FGF-binding protein 1; FGF-BP; FGF-BP1; FGFBP; FGFBP-1; Fgfbp1; FGFP1_HUMAN; Fibroblast growth factor binding protein 1 precursor; Fibroblast growth factor-binding protein 1; HBp17;

抗原和靶标

免疫原:

A synthesized peptide derived from human FGFP1, corresponding to a region within C-terminal amino acids.

基因/基因ID:

文献引用

1). FGFBP1-mediated crosstalk between fibroblasts and pancreatic cancer cells via FGF22/FGFR2 promotes invasion and metastasis of pancreatic cancer. ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021 (PubMed: 34117747) [IF=3.3]

Application: WB    Species: Human    Sample: PANC-1 and Mia PaCa-2 cells

Figure 1. FGFBP1 silencing in PCCs decreased the expression and secretion of FGF22 in human CAFs cocultured with PCCs (A) Efficiency of FGFBP1 knockdown in PANC-1 and Mia PaCa-2 cells evaluated by qRT-PCR. (B) Efficiency of FGFBP1 knockdown in PANC-1 and Mia PaCa-2 cells evaluated by western blot analysis. (C) Heat map of differentially expressed genes in mouse fibroblasts cocultured with FGFBP1-shRNA-transfected PANC-1 cells compared with mouse fibroblasts cocultured with scramble-transfected PANC-1 cells. (D) mRNA level of FGF22 in human CAFs cocultured with FGFBP1-shRNA-transfected PANC-1 or Mia PaCa-2 cells (CAF-P or CAF-M) compared with that in CAFs cocultured with scramble-transfected PANC-1 or Mia PaCa-2 cells. (E) Protein level of FGF22 in CAF-P or CAF-M compared with that in CAFs cocultured with scramble-transfected PANC-1 or Mia PaCa-2 cells are shown. (F) Secretion of FGF22 in culture medium of CAF-P or CAF-M compared with that in culture medium of CAFs cocultured with scramble-transfected PANC-1 or Mia PaCa-2 cells.

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