产品: FGF5 抗体
货号: DF2496
描述: Rabbit polyclonal antibody to FGF5
应用: WB
文献验证: WB
反应: Human, Mouse, Rat
蛋白号: P12034
RRID: AB_2839702

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
FGF5 Antibody detects endogenous levels of total FGF5.
RRID:
AB_2839702
引用格式: Affinity Biosciences Cat# DF2496, RRID:AB_2839702.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FGF 5; FGF-5; FGF5; FGF5_HUMAN; Fibroblast growth factor 5; HBGF 5; HBGF-5; heparin binding growth factor 5; Heparin-binding growth factor 5; Smag 82; Smag-82; TCMGLY;

抗原和靶标

免疫原:

A synthesized peptide derived from human FGF5, corresponding to a region within C-terminal amino acids.

基因/基因ID:
描述:
Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.

研究领域

· Cellular Processes > Cell motility > Regulation of actin cytoskeleton.   (View pathway)

· Environmental Information Processing > Signal transduction > MAPK signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Rap1 signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway.   (View pathway)

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Melanoma.   (View pathway)

· Human Diseases > Cancers: Specific types > Breast cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Gastric cancer.   (View pathway)

文献引用

1). Hair growth predicts a depression-like phenotype in rats as a mirror of stress traceability. NEUROCHEMISTRY INTERNATIONAL, 2021 (PubMed: 34166749) [IF=4.4]

Application: WB    Species: Rat    Sample: Hippocampus tissue

Fig. 5. Down-regulation of the glucocorticoid re- ceptor (GR), fibroblast growth factor 2 (FGF2), brain-derived neurotrophic factor (BDNF) expres- sion in the hippocampus, and fibroblast growth factor 5 (FGF5) expression in the skin of stressed rats. (A) Western blotting and quantification of GR, FGF2, and BDNF expression in the hippocampus; (B) Western blotting and quantification of FGF5 expression in the skin. All data are shown as mean ± SEM; n = 4; * denotes significance compared with control, *p < 0.05, ***p < 0.001.

2). WITHDRAWN: Circ_0041732 regulates tumor progression and angiogenesis by miR-149-5p/FGF5 pathway in triple negative breast cancer. Pathology - Research and Practice, 2021 [IF=2.9]

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