E2F7 Antibody - #DF2444

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产品: E2F7 抗体
货号: DF2444
描述: Rabbit polyclonal antibody to E2F7
应用: WB IHC
文献验证: IHC
反应: Human, Mouse, Rat, Monkey
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
蛋白号: Q96AV8
RRID: AB_2839650

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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实验方案
WB Handbook
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat, Monkey
克隆:
Polyclonal
特异性:
E2F7 Antibody detects endogenous levels of total E2F7.
RRID:
AB_2839650
引用格式: Affinity Biosciences Cat# DF2444, RRID:AB_2839650.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

E2F 7; E2F transcription factor 7; E2F-7; E2f7; E2F7_HUMAN; FLJ12981; Transcription factor E2F7;

抗原和靶标

免疫原:

A synthesized peptide derived from human E2F7, corresponding to a region within N-terminal amino acids.

基因/基因ID:
E2F7(144455)
描述:
Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription (By similarity). Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.

文献引用

1). Upregulation of ECT2 is associated with transcriptional program of cancer stem cells and predicts poor clinical outcome in gastric cancer. Oncology Letters, 2020 (PubMed: 32788941) [IF=2.5]

Application: IHC    Species: human    Sample: gastric cancer

Figure 6. |BUB1 and E2F7 protein expression in human gastric cancer tissues. (A) Representative images depicting immunohistochemical staining of BUB1 (left panel) and E2F7 (right panel) in normal tissues, and well differentiated, moderately differentiated and poorly differentiated gastric cancer tissues.
2). Hsa-miR-195-5p Inhibits Autophagy and Gemcitabine Resistance of Lung Adenocarcinoma Cells via E2F7/CEP55. Biochemical genetics, 2023 (PubMed: 36658310) [IF=2.1]
3). Transcription factor E2F7 activates PKMYT1 to partially suppress adriamycin sensitivity in gastric cancer through the MAPK signaling pathway. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 2024 (PubMed: 38253021) [IF=1.4]

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