CD63 Antibody - #DF2305

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产品: CD63 抗体
货号: DF2305
描述: Rabbit polyclonal antibody to CD63
应用: WB IHC IF/ICC
文献验证: WB, IHC, IF/ICC
反应: Human
蛋白ID: P08962
RRID: AB_2839529

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 50ul RMB¥ 1100 1250 现货
 100ul RMB¥ 2100 2300 现货
 200ul RMB¥ 3000 现货

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CD63 Peptide

1mg
相关下载
抗原肽/阻断肽MS报告
抗原肽/阻断肽HPLC报告
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
CD63 Antibody detects endogenous levels of total CD63.
RRID:
AB_2839529
引用格式: Affinity Biosciences Cat# DF2305, RRID:AB_2839529.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Lysosomal associated membrane protein 3; CD 63; CD63; CD63 antigen (melanoma 1 antigen); CD63 antigen; CD63 antigen melanoma 1 antigen; CD63 molecule; CD63_HUMAN; gp55; Granulophysin; LAMP 3; LAMP-3; LAMP3; LIMP; Lysosomal-associated membrane protein 3; Lysosome associated membrane glycoprotein 3; Mast cell antigen AD1; ME491; Melanoma 1 antigen; Melanoma associated antigen ME491; Melanoma associated antigen MLA1; Melanoma-associated antigen ME491; MGC72893; MLA 1; MLA1; NGA; Ocular melanoma associated antigen; Ocular melanoma-associated antigen; OMA81H; PTLGP40; Tetraspanin 30; Tetraspanin-30; Tspan 30; Tspan-30; TSPAN30;

抗原和靶标

免疫原:

A synthesized peptide derived from human CD63, corresponding to a region within the internal amino acids.

基因/基因ID:
CD63(967)
描述:
This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation

研究领域

· Cellular Processes > Transport and catabolism > Lysosome.   (View pathway)

· Human Diseases > Cancers: Overview > Proteoglycans in cancer.

文献引用

1). M2-like macrophage-derived exosomes facilitate metastasis in non-small-cell lung cancer by delivering integrin αVβ3. MedComm, 2022 (PubMed: 36582304) [IF=9.9]

Application: WB    Species: human    Sample:

FIGURE 3 M2-like macrophage-derived exosomes enhance non-small-cell lung cancer (NSCLC) cell migration and invasion. (A) Western blot of exosomal markers in M2-like macrophage whole-cell lysates and M2-like macrophage-derived exosomes (M2-exos). (B) Nanoparticle tracking analysis of M2-exos. (C) Transmission electron microscope imaging of M2-exos. (D) The uptake of DiI-labeled M2-exos by H1299 cells was detected by confocal microscopy. The cytoskeleton and nucleus of H1299 cells were labeled with FITC-phalloidin and DAPI, respectively. Scale bar, 20 μm. (E and F) A549 and H1299 cells were pretreated for 24 h with phosphate buffered saline (PBS) (control), M2-CM, M2-exos, and M2-CM dexo, and the capacity of cancer cells to migrate and invade was determined using Transwell assays. The left panel displays representative photos, whereas the right panel displays migrating cell counts. The previous experiments were repeated at least three times to ensure the accuracy of the data. All data are presented as the means ± SEMs.
2). Exosome from indoleamine 2,3-dioxygenase-overexpressing bone marrow mesenchymal stem cells accelerates repair process of ischemia/reperfusion-induced acute kidney injury by regulating macrophages polarization. Stem cell research & therapy, 2022 (PubMed: 35902956) [IF=7.5]
3). LncRNA HOXB3OS improves high glucose-mediated podocyte damage and progression of diabetic kidney disease through enhancing SIRT1 mRNA stability. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2025 (PubMed: 39693905) [IF=6.9]
4). Extracellular vesicles delivering nuclear factor I/C for hard tissue engineering: Treatment of apical periodontitis and dentin regeneration. Journal of Tissue Engineering, 2022 (PubMed: 35321254) [IF=6.7]
5). Differential expression analysis of miRNAs in macrophage-derived exosomes in the tuberculosis-infected bone microenvironment. Frontiers in microbiology, 2023 (PubMed: 37601387) [IF=5.2]
6). Improving the process of spermatogenesis in azoospermic mice using spermatogonial stem cells co-cultured with epididymosomes in three-dimensional culture system. Life Sciences, 2022 (PubMed: 36220369) [IF=5.2]
7). Lovastatin attenuates sevoflurane-induced cognitive disorder in aged rats via reducing Aβ accumulation. NEUROCHEMISTRY INTERNATIONAL, 2021 (PubMed: 34048842) [IF=4.4]
8). Hypoxia promotes the expression of Von Willebrand factor in breast cancer cells by up-regulating the transcription factor YY1 and down-regulating the hsa-miR-424. European Journal of Pharmacology, 2022 (PubMed: 36202224) [IF=4.2]
9). Keratinocyte exosomal LOC285194 ameliorates psoriasis by inhibiting the differentiation of CD4+T cells to Th17 cells through regulating miR-211-5p/SIRT1 axis. IUBMB life, 2025 (PubMed: 39736106) [IF=3.7]
10). Schwann cell‑derived exosomes induce bone marrow‑derived mesenchymal stem cells to express Schwann cell markers in vitro. Molecular Medicine Reports, 2020 (PubMed: 32016464) [IF=3.4]
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