| 产品: | USP48 抗体 |
| 货号: | DF2260 |
| 描述: | Rabbit polyclonal antibody to USP48 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 145 kDa; 119kD(Calculated). |
| 蛋白号: | Q86UV5 |
| RRID: | AB_2839489 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2260, RRID:AB_2839489.
展开/折叠
AAH67261; Deubiquitinating enzyme 48; DKFZp762M1713; EC 3.1.2.15; Kiaa4202; MGC132556; MGC14879; RAP1GA1; Synaptic ubiquitin specific protease; synUSP; Ubiquitin carboxyl terminal hydrolase 48; Ubiquitin carboxyl-terminal hydrolase 48; Ubiquitin specific peptidase 48; Ubiquitin specific processing protease 48; Ubiquitin specific protease 31; Ubiquitin specific protease 48; Ubiquitin thioesterase 48; Ubiquitin thiolesterase 48; Ubiquitin-specific-processing protease 48; UBP48_HUMAN; USP31; USP48;
抗原和靶标
- Q86UV5 UBP48_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPRLQLEKAAWRWAETVRPEEVSQEHIETAYRIWLEPCIRGVCRRNCKGNPNCLVGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFLQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDNHACLCSHDKLHPDKISIMKRISEYAADIFYSRYGGGPRLTVKALCKECVVERCRILRLKNQLNEDYKTVNNLLKAAVKGSDGFWVGKSSLRSWRQLALEQLDEQDGDAEQSNGKMNGSTLNKDESKEERKEEEELNFNEDILCPHGELCISENERRLVSKEAWSKLQQYFPKAPEFPSYKECCSQCKILEREGEENEALHKMIANEQKTSLPNLFQDKNRPCLSNWPEDTDVLYIVSQFFVEEWRKFVRKPTRCSPVSSVGNSALLCPHGGLMFTFASMTKEDSKLIALIWPSEWQMIQKLFVVDHVIKITRIEVGDVNPSETQYISEPKLCPECREGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKPDGEKDPDFNQSNGGTKRQKISHQNYIAYQKQVIRRSMRHRKVRGEKALLVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILSDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQVCMPEEGFKGTGLLGH
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q86UV5 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K9 | Ubiquitination | Uniprot | |
| Y162 | Phosphorylation | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| K231 | Ubiquitination | Uniprot | |
| K258 | Ubiquitination | Uniprot | |
| R267 | Methylation | Uniprot | |
| K276 | Ubiquitination | Uniprot | |
| Y326 | Phosphorylation | Uniprot | |
| K368 | Ubiquitination | Uniprot | |
| K376 | Ubiquitination | Uniprot | |
| K381 | Ubiquitination | Uniprot | |
| S394 | Phosphorylation | Uniprot | |
| K395 | Ubiquitination | Uniprot | |
| T398 | Phosphorylation | Uniprot | |
| K425 | Ubiquitination | Uniprot | |
| K468 | Ubiquitination | Uniprot | |
| K473 | Ubiquitination | Uniprot | |
| K505 | Ubiquitination | Uniprot | |
| K518 | Ubiquitination | Uniprot | |
| K523 | Ubiquitination | Uniprot | |
| K551 | Ubiquitination | Uniprot | |
| K555 | Ubiquitination | Uniprot | |
| K568 | Ubiquitination | Uniprot | |
| K576 | Ubiquitination | Uniprot | |
| K583 | Ubiquitination | Uniprot | |
| K587 | Ubiquitination | Uniprot | |
| K596 | Ubiquitination | Uniprot | |
| S620 | Phosphorylation | Uniprot | |
| S627 | Phosphorylation | Uniprot | |
| T628 | Phosphorylation | Uniprot | |
| K669 | Ubiquitination | Uniprot | |
| K674 | Ubiquitination | Uniprot | |
| K681 | Sumoylation | Uniprot | |
| K681 | Ubiquitination | Uniprot | |
| K689 | Ubiquitination | Uniprot | |
| K696 | Ubiquitination | Uniprot | |
| K710 | Ubiquitination | Uniprot | |
| K717 | Ubiquitination | Uniprot | |
| T820 | Phosphorylation | Uniprot | |
| K839 | Ubiquitination | Uniprot | |
| Y859 | Phosphorylation | Uniprot | |
| Y865 | Phosphorylation | Uniprot | |
| K868 | Ubiquitination | Uniprot | |
| S886 | Phosphorylation | Uniprot | |
| S887 | Phosphorylation | Uniprot | |
| S888 | Phosphorylation | Uniprot | |
| S910 | Phosphorylation | Uniprot | |
| K918 | Ubiquitination | Uniprot | |
| Y924 | Phosphorylation | Uniprot | |
| K929 | Ubiquitination | Uniprot | |
| S935 | Phosphorylation | Uniprot | |
| K945 | Ubiquitination | Uniprot | |
| K956 | Acetylation | Uniprot | |
| K956 | Ubiquitination | Uniprot | |
| K1028 | Ubiquitination | Uniprot |
研究背景
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
Cytoplasm. Nucleus.
Widely expressed.
Interacts with TRAF2 and RELA.
Belongs to the peptidase C19 family.
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