规格 价格 库存
 50ul RMB¥ 1800 现货
 100ul RMB¥ 2800 现货

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产品描述

来源:
Mouse
应用:
ELISA 1:10000, WB 1:500-1:2000, IHC 1:200-1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFB1868]
RRID:
AB_2833892
引用格式: Affinity Biosciences Cat# BF0657, RRID:AB_2833892.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ36569; MGC3245; Msi2; MSI2/HOXA9 fusion gene, included; MSI2H; MSI2H_HUMAN; Musashi 2; Musashi homolog 2; Musashi RNA binding protein 2; Musashi, Drosophila, homolog of, 2; Musashi-2; RNA binding protein Musashi homolog 2; RNA-binding protein Musashi homolog 2; WD 40 repeat protein MSI2;

抗原和靶标

免疫原:

Purified recombinant fragment of human MSI2 expressed in E. Coli.

Uniprot:
基因/基因ID:
表达:
Q96DH6 MSI2H_HUMAN:

Ubiquitous; detected at low levels.

序列:
MEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPVAAAAVAAARGSGSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGYH

翻译修饰 - Q96DH6 作为底物

Site PTM Type Enzyme
M1 Acetylation
S6 Phosphorylation
T9 Phosphorylation
S16 Phosphorylation
T32 Phosphorylation
S33 Phosphorylation
K43 Acetylation
K43 Ubiquitination
K59 Ubiquitination
S74 Phosphorylation
K77 Ubiquitination
K89 Ubiquitination
K94 Ubiquitination
K104 Ubiquitination
Y129 Phosphorylation
K135 Ubiquitination
K145 Ubiquitination
K166 Ubiquitination
K178 Ubiquitination
R197 Methylation
R199 Methylation
R201 Methylation
R228 Methylation
R261 Methylation

研究背景

功能:

RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

翻译修饰:

Phosphorylated.

细胞定位:

Cytoplasm.
Note: Associated with polysomes.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous; detected at low levels.

蛋白家族:

Belongs to the Musashi family.

研究领域

· Genetic Information Processing > Translation > mRNA surveillance pathway.

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