| 产品: | NR2C2 抗体 |
| 货号: | DF2219 |
| 描述: | Rabbit polyclonal antibody to NR2C2 |
| 应用: | ELISA(peptide) |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 蛋白ID: | P49116 |
| RRID: | AB_2839450 |
产品描述
来源:
Rabbit
反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
NR2C2 Antibody detects endogenous levels of total NR2C2.
RRID:
AB_2839450
引用格式: Affinity Biosciences Cat# DF2219, RRID:AB_2839450.
引用格式: Affinity Biosciences Cat# DF2219, RRID:AB_2839450.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
hTAK1; Nr2c2; NR2C2_HUMAN; Nuclear hormone receptor TR4; Nuclear receptor subfamily 2 group C member 2; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; TAK1; Testicular nuclear receptor 4; Testicular receptor 4; TR2R1; TR4; TR4 nuclear hormone receptor;
抗原和靶标
免疫原:
A synthesized peptide derived from human NR2C2, corresponding to a region within the internal amino acids.
基因/基因ID:
描述:
Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear recptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation
限制条款
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