产品: Tubulin alpha 抗体
货号: T0033
描述: Mouse monoclonal antibody to Tubulin alpha
应用: WB ELISA
文献验证: WB
反应: Human, Mouse, Zebrafish, Rabbit
蛋白号: P68366
RRID: AB_2839424

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   规格 价格 库存
 50ul RMB¥ 450 现货
 100ul RMB¥ 750 现货
 200ul RMB¥ 1000 现货

货期: 当天发货

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产品描述

来源:
Mouse
应用:
WB 1:3000-1:10000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Zebrafish, Rabbit
克隆:
Monoclonal [F794]
特异性:
The α-tubulin antibody can detects ebrafish endogenousα-tubulin protein.
RRID:
AB_2839424
引用格式: Affinity Biosciences Cat# T0033, RRID:AB_2839424.
偶联:
Unconjugated.
纯化:
affinity purification.
保存:
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Do not aliquot the antibody. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

TUBA4A, Alpha-tubulin 1, TUBA1, Testis-specific alpha-tubulin, Tubulin, alpha 4a, H2-ALPHA, Tubulin alpha-1 chain, Tubulin alpha-4 chain, Tubulin alpha-4A chain, Tubulin H2-alpha, Tubulin, alpha 1

抗原和靶标

免疫原:

Peptide from Zebrafish alpha tubulin.

基因/基因ID:
描述:
Tubulin is one of several members of a small family of globular proteins. The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins. The most common members of the tubulin family are α-tubulin and β-tubulin, the proteins that make up microtubules. Each has a molecular weight of approximately 55 KD. Microtubules are assembled from dimers of α- and β-tubulin.

研究领域

· Cellular Processes > Transport and catabolism > Phagosome.   (View pathway)

· Cellular Processes > Cell growth and death > Apoptosis.   (View pathway)

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

· Cellular Processes > Cellular community - eukaryotes > Gap junction.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Pathogenic Escherichia coli infection.

文献引用

1). Loss of Smek1 Induces Tauopathy and Triggers Neurodegeneration by Regulating Microtubule Stability. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024 (PubMed: 39206808) [IF=15.1]

2). Downregulation of OPN3 Gene Induces Ferroptosis, Apoptosis, and Pyroptosis of Human Dermal Fibroblasts In Vitro. The Journal of investigative dermatology, 2024 (PubMed: 38548258) [IF=5.7]

3). Protection of Ficus pandurata Hance against acute alcohol-induced liver damage in mice via suppressing oxidative stress, inflammation, and apoptosis. Journal of Ethnopharmacology, 2021 (PubMed: 33915134) [IF=4.8]

Application: WB    Species: mice    Sample: liver tissues

Fig. 5. Effects of FPHAP on the oxidative stress and Nrf2/HO-1 signaling pathway of liver tissues in acute ALD mice. (A) Levels of ROS, MDA, SOD and GSH, (B) Protein expressions of Nrf2, HO-1, NQO-1 in liver tissues of mice treated with or without Silybin, FPHAP (12 g/kg), FPHAP (24 g/kg), and FPHAP (48 g/kg). Data (n = 8) are expressed as mean ± SEM. ##p < 0.01, ###p < 0.001, comparing with normal; *p < 0.05,**p < 0.01, ***p < 0.001, comparing with model.

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