PAX4 Antibody - #BF0438
产品: | PAX4 抗体 |
货号: | BF0438 |
描述: | Mouse monoclonal antibody to PAX4 |
应用: | WB ELISA |
反应: | Human |
分子量: | 38kDa; 38kD(Calculated). |
蛋白号: | O43316 |
RRID: | AB_2833880 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# BF0438, RRID:AB_2833880.
展开/折叠
KPD; MGC129960; MODY9; Paired box 4; Paired box gene 4; paired box homeotic gene 4; Paired box protein Pax-4; Paired domain gene 4; Pax4; PAX4_HUMAN;
抗原和靶标
Purified recombinant fragment of human PAX4 expressed in E. Coli.
- O43316 PAX4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHQDGISSMNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVLRALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWDCGSFLLPVIAPSCVDVAWPCLDASLAHHLIGGAGKATPTHFSHWP
翻译修饰 - O43316 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T26 | Phosphorylation | Uniprot | |
T64 | Phosphorylation | Uniprot |
研究背景
Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Nucleus.
Belongs to the paired homeobox family.
研究领域
· Human Diseases > Endocrine and metabolic diseases > Maturity onset diabetes of the young.
限制条款
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