产品: Asparagine synthetase 抗体
货号: DF7398
描述: Rabbit polyclonal antibody to Asparagine synthetase
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Rabbit, Dog, Chicken, Xenopus
蛋白号: P08243
RRID: AB_2839336

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 50ul RMB¥ 1250 现货
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 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
Asparagine synthetase Antibody detects endogenous levels of total Asparagine synthetase.
RRID:
AB_2839336
引用格式: Affinity Biosciences Cat# DF7398, RRID:AB_2839336.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

asnS; ASNS_HUMAN; ASNSD; Asparagine synthetase [glutamine-hydrolyzing]; Asparagine synthetase; Cell cycle control protein TS11; Glutamine dependent asparagine synthetase 3; Glutamine dependent asparagine synthetase; Glutamine hydrolyzing; Glutamine-dependent asparagine synthetase; OTTHUMP00000024510; OTTHUMP00000204938; OTTHUMP00000204939; OTTHUMP00000204940; OTTHUMP00000204941; OTTHUMP00000204942; TS11; TS11 cell cycle control protein;

抗原和靶标

免疫原:

A synthesized peptide derived from human Asparagine synthetase, corresponding to a region within N-terminal amino acids.

基因/基因ID:
描述:
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene.

研究领域

· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

文献引用

1). ATF4 inhibits tumor development and mediates p-GCN2/ASNS upregulation in colon cancer. Scientific reports, 2024 (PubMed: 38844625) [IF=3.8]

2). Identification of key genes associated with the progression of liver fibrosis to hepatocellular carcinoma based on iTRAQ proteomics and GEO database. Annals of hepatology, 2022 (PubMed: 35124283) [IF=3.7]

Application: WB    Species: human    Sample:

Fig. 8. The expression and survival analysis of ALDH2, SLC27A5 and ASNS in patients with HCC and validation. (A) The expression of ALDH2, SLC27A5 and ASNS in HCC. (B) The expression of ALDH2, SLC27A5 and ASNS in different stages of HCC. (C) Survival analysis of ALDH2, SLC27A5 and ASNS. (D) WB analysis of ALDH2, SLC27A5 and ASNS. (E) qRT-PCR analysis of ALDH2, SLC27A5 and ASNS.

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