SULT2A1 Antibody - #DF7371

(5)  
产品: SULT2A1 抗体
货号: DF7371
描述: Rabbit polyclonal antibody to SULT2A1
应用: WB IHC
反应: Human, Mouse, Rat
预测: Bovine, Horse, Rabbit
分子量: 34kDa; 34kD(Calculated).
蛋白号: Q06520
RRID: AB_2839309

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 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Bovine(83%), Horse(83%), Rabbit(83%)
克隆:
Polyclonal
特异性:
SULT2A1 Antibody detects endogenous levels of total SULT2A1.
RRID:
AB_2839309
引用格式: Affinity Biosciences Cat# DF7371, RRID:AB_2839309.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Alcohol/hydroxysteroid sulfotransferase; Bile salt sulfotranasferase 2A1; Bile salt sulfotransferase; Dehydroepiandrosterone sulfotransferase; DHEA ST; DHEA sulfotranasferase; DHEA-ST; DHEAS; EC 2.8.2.14; Hst; hSTa; Hydroxysteroid sulfotransferase; ST2; ST2A1; ST2A1_HUMAN; ST2A3; STD; sulfotranasferase, dehydroepiandrosterone-preferring; Sulfotransferase 2A1; Sulfotransferase family 2A, dehydroepiandrosterone-preferring, member 1; Sulfotransferase family cytosolic 2A dehydroepiandrosterone (DHEA) preferring member 1; Sult2a1;

抗原和靶标

免疫原:
Uniprot:

Q06520(ST2A1_HUMAN) >>Visit HPA database.

基因/基因ID:
SULT2A1(6822)
表达:
Q06520 ST2A1_HUMAN:

Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney.

描述:
This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome.
序列:
MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Horse
83
Bovine
83
Rabbit
83
Pig
75
Sheep
75
Xenopus
75
Dog
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q06520 作为底物

Site PTM Type Enzyme
S20 Phosphorylation
T90 Phosphorylation
K135 Acetylation
K177 Acetylation
S183 Phosphorylation
Y184 Phosphorylation
Y231 Phosphorylation
S251 Phosphorylation

研究背景

功能:

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands.

翻译修饰:

The N-terminus is blocked.

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney.

亚基结构:

Homodimer.

蛋白家族:

Belongs to the sulfotransferase 1 family.

研究领域

· Human Diseases > Cancers: Overview > Chemical carcinogenesis.

· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.

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