PACAP receptor Antibody - #DF7197

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产品: PACAP receptor 抗体
货号: DF7197
描述: Rabbit polyclonal antibody to PACAP receptor
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: P41586
RRID: AB_2839149

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
PACAP receptor Antibody detects endogenous levels of total PACAP receptor.
RRID:
AB_2839149
引用格式: Affinity Biosciences Cat# DF7197, RRID:AB_2839149.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ADCYAP1 R1; ADCYAP1R 1; ADCYAP1R1; Adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1; Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC 1; PAC1; PAC1R; PACAP receptor 1; PACAP type I receptor; PACAP-R-1; PACAP-R1; PACAP1 R; PACAPR; PACAPRI; PACR_HUMAN; Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; Pituitary adenylate cyclase activating polypeptide receptor; Pituitary adenylate cyclase activating polypeptide type I receptor precursor; Pituitary adenylate cyclase-activating polypeptide 1, receptor for; Pituitary adenylate cyclase-activating polypeptide type I receptor; pvr1;

抗原和靶标

免疫原:

A synthesized peptide derived from human PACAP receptor, corresponding to a region within C-terminal amino acids.

基因/基因ID:
ADCYAP1R1(117)
描述:
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.

研究领域

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Organismal Systems > Environmental adaptation > Circadian entrainment.

· Organismal Systems > Endocrine system > Insulin secretion.   (View pathway)

· Organismal Systems > Endocrine system > Renin secretion.

文献引用

1). PACAP inhibition alleviates neuropathic pain by modulating Nav1.7 through the MAPK/ERK signaling pathway in a rat model of chronic constriction injury. Neuropeptides, 2023 (PubMed: 36842389) [IF=2.5]

Application: WB    Species: Rat    Sample:

Fig. 2. The comparison of change mechanical pain threshold and mRNA and protein expression in the trigeminal ganglion (TG) among non-injected chronic constriction injury of the infraorbital nerve (ION-CCI) rats, NS-injected negative ION-CCI rats, and pituitary adenylate cyclase-activating polypeptide (PACAP) 6–38 injected rats. (A) The mechanical threshold of the three groups was recorded 1 h before and 4 h after the injection. Data suggested that the mechanical threshold of the PACAP 6–38-injected group increased compared with that of the other two groups and attained the highest level at 4 h after the injection. In contrast, the other two groups presented almost no change. Data represent mean with errors, n = 6, **p

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