产品: IGFBP1 抗体
货号: DF7130
描述: Rabbit polyclonal antibody to IGFBP1
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Horse, Rabbit, Dog, Xenopus
蛋白号: P08833
RRID: AB_2839084

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:100
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
IGFBP1 Antibody detects endogenous levels of total IGFBP1.
RRID:
AB_2839084
引用格式: Affinity Biosciences Cat# DF7130, RRID:AB_2839084.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

AFBP; Alpha pregnancy associated endometrial globulin; Amniotic fluid binding protein; Binding protein 25; Binding protein 26; Binding protein 28; Growth hormone independent binding protein; hIGFBP 1; hIGFBP1; IBP 1; IBP-1; IBP1; IBP1_HUMAN; IGF binding protein 1; IGF BP25; IGF-binding protein 1; IGFBP 1; IGFBP-1; IGFBP1; Insulin like growth factor binding protein 1; Insulin-like growth factor-binding protein 1; Placental protein 12; PP 12; PP12;

抗原和靶标

免疫原:

A synthesized peptide derived from human IGFBP1, corresponding to a region within C-terminal amino acids.

基因/基因ID:
描述:
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

文献引用

1). The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia. International journal of molecular sciences, 2023 (PubMed: 36982197) [IF=5.6]

Application: WB    Species: Rat    Sample:

Figure 5. Function of 15-PGDH. (A) PGE2 levels in cell lysates were quantified by ELISA. The results are representative of at least three independent experiments. (B,C) F-actin staining revealed cytoskeletal changes in dhESCs and HTR8 cells in the NC (normal control) group and SW033291 group. (D,E) Western blot assays show the relative levels of EMT markers and HLA-G in Jeg3. (F,G) Western blot assays show the relative levels of EMT markers and decidualization markers in hESC. Each experiment was independently performed three times. CTB: cytotrophoblast; EVT: extravillous trophoblasts; EMT: epithelial–mesenchymal transition; DSC: decidual stromal cell. The experiment was repeated 3 times independently. Band intensities were quantified and normalized to the GAPDH values. Values are the mean ± SD.

2). A prospective diagnostic and prognostic biomarker for hepatocellular carcinoma that functions in glucose metabolism regulation: Solute carrier family 37 member 3. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2023 (PubMed: 36773462) [IF=4.2]

3). O-Fucosylation of BMP1 promotes endometrial decidualization by activating BMP/Smad signaling pathway. Biology of reproduction, 2023 (PubMed: 37338142) [IF=3.1]

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