IL18R1 Antibody - #DF7059

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产品: IL18R1 抗体
货号: DF7059
描述: Rabbit polyclonal antibody to IL18R1
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig
蛋白号: Q13478
RRID: AB_2839015

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MSDS
说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IHC 1:50-1:100, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
IL18R1 Antibody detects endogenous levels of total IL18R1.
RRID:
AB_2839015
引用格式: Affinity Biosciences Cat# DF7059, RRID:AB_2839015.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CD218 antigen-like family member A; CD218a; CDw218a; CDw218a antigen; IL 1Rrp; IL-18R-1; IL-18R1; IL-1Rrp; IL1 receptor related protein; IL1 receptor-related protein; IL18R_HUMAN; IL18R1; IL18RA; Il18ralpha; IL1R-rp; IL1RRP; Interleukin 18 receptor 1; Interleukin 18 receptor, alpha chain; Interleukin-18 receptor 1;

抗原和靶标

免疫原:

A synthesized peptide derived from human IL18R1, corresponding to a region within the internal amino acids.

基因/基因ID:
IL18R1(8809)
描述:
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. [provided by RefSeq, Jul 2008]

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Environmental Information Processing > Signal transduction > TNF signaling pathway.   (View pathway)

· Human Diseases > Immune diseases > Inflammatory bowel disease (IBD).

文献引用

1). The Expression of Cytokine Profiles and Related Receptors in Idiopathic Inflammatory Myopathies. Frontiers in Pharmacology, 2022 (PubMed: 35517781) [IF=5.6]

Application: WB    Species: Human    Sample: muscle tissues

FIGURE 4 Expression of IL18R1 in the muscle tissues and blood of IIMs patients. (A) The expression of IL18R1 mRNA in the muscle tissues of 19 DM patients and 16 HC. (B) Western blot showed the expression of IL18R1 protein in muscle tissues of 8 DM patients and 5 HC. (C) Flow cytometry analysis the expression of IL18R1 on lymphocytes among 19 untreated IIMs (9 anti-MDA5 positive) patients, 24 treated IIMs patients and 18 HC. Unpaired t-test was used for comparison. Pre-IIMs: IIMs before treatment; Post-IIMs: IIMs treatment.

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