BTC Antibody - #DF7038

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产品: BTC 抗体
货号: DF7038
描述: Rabbit polyclonal antibody to BTC
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Bovine, Horse, Sheep, Rabbit
蛋白号: P35070
RRID: AB_2838994

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
BTC Antibody detects endogenous levels of total BTC.
RRID:
AB_2838994
引用格式: Affinity Biosciences Cat# DF7038, RRID:AB_2838994.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Betacellulin; Betacellulin precursor; BTC; BTC_HUMAN; OTTHUMP00000160600; OTTHUMP00000219057; Probetacellulin;

抗原和靶标

免疫原:

A synthesized peptide derived from human BTC, corresponding to a region within N-terminal amino acids.

基因/基因ID:
BTC(685)
描述:
The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.

研究领域

· Environmental Information Processing > Signal transduction > ErbB signaling pathway.   (View pathway)

文献引用

1). HDAC1 in the Ovarian Granulosa Cells of Tan Sheep Improves Cumulus Cell Expansion and Oocyte Maturation Independently of the EGF-like Growth Factors. Biology, 2022 (PubMed: 36290368) [IF=4.2]

Application: WB    Species: sheep    Sample:

Figure 3. The effect of HDAC1 inhibition on the expression and secretion of EGF-like growth factors in cultured granulosa cells from Tan sheep. (A,B): Analysis of the effect of the LH time on HDAC1 protein expression. (C–E): Screening the inhibitory efficiency of pyroxamide, a specific inhibitor of HDAC1, regarding the levels of proteins, as indicated by acetylated lysin. (F,G): The expression levels of the EGF-like growth factors in response to pyroxamide treatment. (H): The expression levels of the respective EGF-like growth factors detected by immunofluorescence. The green fluorescence indicated AREG, EREG and BTC, and the blue fluorescence indicated Hoechst staining to mark the nucleus. The scale was 100 μm; the rightmost column contains an enlarged view of the merged figure. (I): The respective levels of the secreted AREG, EREG and BTC in the cultured granulosa cells of the Tan sheep. * p < 0.05; ** p < 0.01; *** p < 0.001; ns: Indicate no significant differences, n = 3.
2). Inhibition of HDAC4 in granulosa cells improves co-cultured porcine oocyte maturation in vitro independently of LH. Development (Cambridge, England), 2025 (PubMed: 40066659) [IF=3.7]
3). Machine learning-based screening for biomarkers of psoriasis and immune cell infiltration. European journal of dermatology : EJD, 2023 (PubMed: 37431117) [IF=2.0]

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