UHRF2 Antibody - #DF6930

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产品: UHRF2 抗体
货号: DF6930
描述: Rabbit polyclonal antibody to UHRF2
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: Q96PU4
RRID: AB_2838889

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:20-1:50
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
UHRF2 Antibody detects endogenous levels of total UHRF2.
RRID:
AB_2838889
引用格式: Affinity Biosciences Cat# DF6930, RRID:AB_2838889.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

DKFZp434B0920; DKFZp686G0837; E3 ubiquitin-protein ligase UHRF2; MGC33463; Np95 like RING finger protein; Np95-like ring finger protein; Np95/ICBP90 like RING finger protein; Np95/ICBP90-like RING finger protein; Nuclear protein 97; Nuclear zinc finger protein Np97; RING finger protein 107; RNF 107; RP11-472F14.2; Ubiquitin like containing PHD and RING finger domains protein 2; Ubiquitin-like PHD and RING finger domain-containing protein 2; Ubiquitin-like-containing PHD and RING finger domains protein 2; Uhrf2; UHRF2_HUMAN; URF 2;

抗原和靶标

免疫原:

A synthesized peptide derived from human UHRF2, corresponding to a region within the internal amino acids.

基因/基因ID:
UHRF2(115426)
描述:
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]

文献引用

1). The prognostic value of ubiquitin/ubiquitin-like-related genes along with immune cell infiltration and clinicopathological features in osteosarcoma. Journal of orthopaedic surgery and research, 2024 (PubMed: 38879525) [IF=2.8]

Application: WB    Species: Human    Sample:

Fig. 8 The mRNA and protein expression of TRIM8 and UHRF2 in cell lines. The mRNA expression of TRIM8 (A) and UHRF2 (B) relative to that of β-actin in osteosarcoma and osteoblast cells by qRT-PCR (2−ΔΔCT method, mean ± standard error of the mean). C Western blotting analysis of TRIM8 and UHRF2 expression. The protein expression of TRIM8 (D) and UHRF2 (E) relative to that of β-actin in osteosarcoma and osteoblast cells was determined by Western blotting analysis (mean ± standard error of the mean)

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