| 产品: | TOR1A 抗体 |
| 货号: | DF6796 |
| 描述: | Rabbit polyclonal antibody to TOR1A |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 蛋白号: | O14656 |
| RRID: | AB_2838758 |
产品描述
来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
TOR1A Antibody detects endogenous levels of total TOR1A.
RRID:
AB_2838758
引用格式: Affinity Biosciences Cat# DF6796, RRID:AB_2838758.
引用格式: Affinity Biosciences Cat# DF6796, RRID:AB_2838758.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
DQ2; Dystonia 1; Dystonia 1 protein; Dystonia 1 torsion; Dyt1; TOR1A; TOR1A_HUMAN; Torsin 1A; Torsin A; Torsin family 1 member A; Torsin family 1, member A (torsin A); Torsin-1A;
抗原和靶标
免疫原:
A synthesized peptide derived from human TOR1A, corresponding to a region within the internal amino acids.
基因/基因ID:
描述:
The neurological condition Dystonia is associated with sustained muscle contractions and abnormal posturing (1). TorsinA, torsinB, torp2A and torp3A belong to the family of ATPases associated with cellular activites (AAA+) and mutations in torsinA cause early onset dystonia (2). TorsinA has been shown to suppress intracellular protein aggregation in C. elegans and possesses chaperon activity. Interestingly, torsinA is highly expressed in dopaminergic neurons and associates with alpha-synuclein in Lewy bodies, which pathologically characterize Parkinson's Disease (3-5).
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