GABRA2 Antibody - #DF6626

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产品: GABRA2 抗体
货号: DF6626
描述: Rabbit polyclonal antibody to GABRA2
应用: WB IHC IF/ICC
文献验证: WB, IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: P47869
RRID: AB_2838588

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
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说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
GABRA2 Antibody detects endogenous levels of total GABRA2.
RRID:
AB_2838588
引用格式: Affinity Biosciences Cat# DF6626, RRID:AB_2838588.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

GABA A receptor subunit alpha 2; GABA; GABA(A) receptor subunit alpha 2; GABA(A) receptor subunit alpha-2; GABR A2; GABRA 2; GABRA2; GABRA2 protein; Gamma aminobutyric acid (GABA) A receptor alpha 2; Gamma aminobutyric acid A receptor alpha 2; Gamma aminobutyric acid receptor alpha 2 subunit; Gamma aminobutyric acid receptor subunit alpha 2; Gamma-aminobutyric acid receptor subunit alpha-2; GBRA2_HUMAN;

抗原和靶标

免疫原:

A synthesized peptide derived from human GABRA2, corresponding to a region within N-terminal amino acids.

基因/基因ID:
GABRA2(2555)
描述:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Human Diseases > Substance dependence > Morphine addiction.

· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling.   (View pathway)

· Organismal Systems > Nervous system > GABAergic synapse.

· Organismal Systems > Sensory system > Taste transduction.

文献引用

1). Myristic acid alleviates hippocampal aging correlated with GABAergic signaling. Frontiers in Nutrition, 2022 (PubMed: 36159502) [IF=4.0]

Application: IHC    Species: Mouse    Sample: hippocampus

Figure 4 Validation of GABRB2 and GABRA2 expression by IHC of hippocampus in aging mice. (A) IHC of GABRB2 and GABRA2 in the hippocampus between 3M and 22M group. The magnifications and scale bars were shown in (A). (B,C) Relative expressions of GABRB2 and GABRA2 were calculated by IHC. Data were represented as mean ± SD and were analyzed by Student t-test.
2). Electroacupuncture Suppresses CCI-Induced Neuropathic Pain through GABAA Receptors. Evidence-based complementary and alternative medicine : eCAM, 2022 (PubMed: 36248405)

Application: WB    Species: Rat    Sample:

Figure 3

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