SCARB1 Antibody - #DF6479

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产品: SCARB1 抗体
货号: DF6479
描述: Rabbit polyclonal antibody to SCARB1
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Horse, Sheep, Rabbit, Dog
蛋白号: Q8WTV0
RRID: AB_2838441

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
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说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
SCARB1 Antibody detects endogenous levels of total SCARB1.
RRID:
AB_2838441
引用格式: Affinity Biosciences Cat# DF6479, RRID:AB_2838441.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CD36 and LIMPII analogous 1; CD36; CD36 Antigen like 1; CD36 antigen-like 1; CD36L1; CLA 1; CLA-1; CLA1; Collagen type I receptor; HDLQTL6; MGC138242; SCARB1; Scavebger Receptor Class B Member 1; Scavenger receptor class B member 1; Scavenger Receptor Class B Type 1; SCRB1_HUMAN; SR BI; SR-BI; SRB1; SRBI; Thrombospondin receptor like 1; thrombospondin receptor-like 1;

抗原和靶标

免疫原:

A synthesized peptide derived from human SCARB1, corresponding to a region within the internal amino acids.

基因/基因ID:
SCARB1(949)
描述:
The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

研究领域

· Cellular Processes > Transport and catabolism > Phagosome.   (View pathway)

· Human Diseases > Infectious diseases: Viral > Hepatitis C.

· Organismal Systems > Endocrine system > Ovarian steroidogenesis.

· Organismal Systems > Endocrine system > Aldosterone synthesis and secretion.

· Organismal Systems > Digestive system > Fat digestion and absorption.

· Organismal Systems > Digestive system > Vitamin digestion and absorption.

· Organismal Systems > Digestive system > Cholesterol metabolism.

文献引用

1). Brain-specific loss of Abcg1 disturbs cholesterol metabolism and aggravates pyroptosis and neurological deficits after traumatic brain injury. Brain pathology (Zurich, Switzerland), 2023 (PubMed: 36271611) [IF=5.8]

Application: WB    Species: Mouse    Sample: brain

FIGURE 2 The expression of cholesterol metabolism-related proteins in the cortex post-TBI. (A) Representative western blotting bands of ABCA1, ABCG1, ABCG4, SCARB1, ApoE, LCAT, RXRalpha, PPARgamma, LXRalpha, and beta-actin in the cortex at the indicated time point post-TBI. (B) The relative optical densitometric quantification of the proteins was normalized against beta-actin. (C, D) A panoramic view of brain slice pointed out the location of injured cortical brain regions used for staining and cell counts. Distribution and semi-quantitative analysis of ABCA1 and ABCG1 in the injured cortex on Day 3 after TBI. Examples of co-localization of ABCA1/ABCG1 with the neuron marker NeuN, the astrocyte marker GFAP, and the microglia marker Iba-1 using white arrows. (E, F) The immunohistochemical staining and semi-quantitative analysis of ABCA1 and ABCG1 in the injured and normal cortex in the human brain. Examples of ABCA1/ABCG1-positive cell using white arrows. Data are mean ± SEM; *p 
2). Huanglian Jiedu decoction inhibits vascular smooth muscle cell-derived foam cell formation by activating autophagy via suppressing P2RY12. Journal of ethnopharmacology, 2024 (PubMed: 38561055) [IF=4.8]
3). Silica-coated magnetic nanoparticles labeled endothelial progenitor cells alleviate ischemic myocardial injury and improve long-term cardiac function with magnetic field guidance in rats with myocardial infarction. JOURNAL OF CELLULAR PHYSIOLOGY, 2019 (PubMed: 30982985) [IF=4.5]

Application: WB    Species: rat    Sample: EPCs

FIGURE 6| (a) Representative Masson staining images of the heart papillary muscle cross‐sectional scan images, and infarct rate of the different groups. (b) Upper panel: Bar graphs of LVEF and LVFS before and at 4 weeks after the transplantation of EPCs in the different groups.Lower panel: Western blots analysis of the expression of ANP and BNP in the different groups.
4). A Novel Rat Model of Patellofemoral Osteoarthritis Due to Patella Baja, or Low-Lying Patella. MEDICAL SCIENCE MONITOR, 2019 (PubMed: 30979862) [IF=2.2]

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