RBP4 Antibody - #BF0247

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产品: RBP4 抗体
货号: BF0247
描述: Mouse monoclonal antibody to RBP4
应用: WB IHC IF/ICC ELISA FACS
反应: Human
分子量: 23kDa; 23kD(Calculated).
蛋白号: P02753
RRID: AB_2833784

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   规格 价格 库存
 50ul RMB¥ 1800 现货
 100ul RMB¥ 2800 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse
应用:
ELISA 1:10000, WB 1:500-1:2000, IHC 1:200-1:1000, IF/ICC 1:200-1:1000, FCM 1:200-1:400
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFB1760]
特异性:
RBP4 antibody detects endogenous levels of total RBP4.
RRID:
AB_2833784
引用格式: Affinity Biosciences Cat# BF0247, RRID:AB_2833784.
偶联:
Unconjugated. 130
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

OTTHUMP00000020114; OTTHUMP00000020115; OTTHUMP00000020116; Plasma retinol binding protein 4; Plasma retinol-binding protein; Plasma retinol-binding protein(1-176); PRBP; PRO2222; RBP; RBP4; RDCCAS; RET4_HUMAN; Retinol binding protein 4; Retinol binding protein 4 interstitial; Retinol binding protein 4 plasma;

抗原和靶标

免疫原:

Purified recombinant fragment of human RBP4 expressed in E. Coli.

Uniprot:

P02753(RET4_HUMAN) >>Visit HPA database.

基因/基因ID:
RBP4(5950)
表达:
P02753 RET4_HUMAN:

Detected in blood plasma and in urine (at protein level).

描述:
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. (provided by RefSeq)
序列:
MKWVWALLLLAALGSGRAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL

研究背景

功能:

Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane.

细胞定位:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Detected in blood plasma and in urine (at protein level).

亚基结构:

Interacts with TTR. Interaction with TTR prevents its loss by filtration through the kidney glomeruli (Probable). Interacts with STRA6.

蛋白家族:

Belongs to the calycin superfamily. Lipocalin family.

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