产品: FSHR 抗体
货号: DF6422
描述: Rabbit polyclonal antibody to FSHR
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: P23945
RRID: AB_2838385

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
FSHR Antibody detects endogenous levels of total FSHR.
RRID:
AB_2838385
引用格式: Affinity Biosciences Cat# DF6422, RRID:AB_2838385.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; Fshr; FSHR_HUMAN; FSHRO; LGR1; MGC141667; MGC141668; ODG1; ovarian dysgenesis 1;

抗原和靶标

免疫原:

A synthesized peptide derived from human FSHR, corresponding to a region within the internal amino acids.

基因/基因ID:
描述:
FSHR, also named as LGR1, belongs to the G-protein coupled receptor 1 family and FSH/LSH/TSH subfamily. FSHR is a receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Defects in FSHR are a cause of ovarian dysgenesis type 1 (ODG1). Defects in FSHR are a cause of ovarian hyperstimulation syndrome (OHSS). The antibody is special to FSHR.

研究领域

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Organismal Systems > Endocrine system > Ovarian steroidogenesis.

文献引用

1). Altered m6A modification is involved YAP-mediated apoptosis response in 4-vinylcyclohexene diepoxide induced ovotoxicity. Ecotoxicology and environmental safety, 2023 (PubMed: 37393819) [IF=6.2]

Application: WB    Species: Rat    Sample:

Fig. 3. Effect of follicular depletion induced by VCD on reproductive endocrine changes.(A-B) Levels of AMH and FSH in the serum of rats in the two groups.* **p 

2). Protective effects of electroacupuncture on polycystic ovary syndrome in rats: Down-regulating Alas2 to inhibit apoptosis, oxidative stress, and mitochondrial dysfunction in ovarian granulosa cells. Tissue and Cell, 2023 (PubMed: 37075681) [IF=2.7]

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