产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6352, RRID:AB_2838316.
展开/折叠
Activated protein C binding protein; Activated protein C-binding protein; Anticardiolipin cofactor; APC inhibitor; Apo-H; APOH; APOH_HUMAN; apolipoprotein H (beta-2-glycoprotein I); Apolipoprotein H; B2G1; B2GP1; B2GPI; Beta 2 glycoprotein I; Beta 2 glycoprotein I precursor; Beta(2)GPI; Beta-2-glycoprotein 1; Beta-2-glycoprotein I; BG; Glycoprotein 1, beta-2; Glycoprotein I, beta-2; OTTMUSP00000003033;
抗原和靶标
- P02749 APOH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P02749 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N162 | N-Glycosylation | Uniprot | |
| N183 | N-Glycosylation | Uniprot | |
| N193 | N-Glycosylation | Uniprot | |
| N253 | N-Glycosylation | Uniprot | |
| T272 | Phosphorylation | Uniprot | |
| C300 | S-Nitrosylation | Uniprot | |
| K301 | Methylation | Uniprot |
研究背景
Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
N- and O-glycosylated.also reports glycosylation on 'Asn-188' for their allele.
Secreted.
Expressed by the liver and secreted in plasma.
研究领域
· Organismal Systems > Digestive system > Cholesterol metabolism.
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