AMACR Antibody - #DF6265

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产品: AMACR 抗体
货号: DF6265
描述: Rabbit polyclonal antibody to AMACR
应用: WB IHC IF/ICC
文献验证: IHC
反应: Human, Mouse, Rat
蛋白号: Q9UHK6
RRID: AB_2838231

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
AMACR Antibody detects endogenous levels of total AMACR.
RRID:
AB_2838231
引用格式: Affinity Biosciences Cat# DF6265, RRID:AB_2838231.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

2 arylpropionyl CoA epimerase; 2 methylacyl CoA racemase; 2-methylacyl-CoA racemase; Alpha methylacyl CoA racemase; Alpha methylacyl Coenzyme A racemase; Alpha methylacyl-CoA racemase deficiency, included; Alpha-methylacyl-CoA racemase; Amacr; AMACR deficiency, included; AMACR_HUMAN; CBAS4; Da1-8; EC 5.1.99.4; Macr1; Methylacyl CoA racemase alpha; RACE; RM;

抗原和靶标

免疫原:

A synthesized peptide derived from human AMACR, corresponding to a region within the internal amino acids.

基因/基因ID:
AMACR(23600)
描述:
α-methylacyl-CoA racemase (AMACR), an enzyme localized in peroxisomes and mitochondria, is involved in the β-oxidation of branched-chain fatty acids and fatty acid derivatives (1). AMACR has been reported to be a biomarker for prostate cancer (2-4). The expression of AMACR is also related to other types of cancers such as hepatocellular carcinoma (1), noninvasive bladder cancer (5), colorectal cancer (6) and gastric adenocarcinoma (7).

研究领域

· Cellular Processes > Transport and catabolism > Peroxisome.   (View pathway)

· Metabolism > Lipid metabolism > Primary bile acid biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

文献引用

1). HMGCS2 and AMACR as potential targets linking mitochondrial dysfunction and ulcerative colitis. Scientific reports, 2024 (PubMed: 39738583) [IF=3.8]

Application: IHC    Species: human    Sample:

Fig. 6 Expression of signature MitoDEGs in UC patients (A) RT-qPCR analysis of two signature MitoDEGs in clinical samples. (B, C) Immunohistochemical plots showing two signature MitoDEGs in healthy and UC. (D) Analysis of the correlation between HMGCS2 expression level and ESR, CRP, WBC, FDP, D-D, FIB and PLT, and the correlation between AMACR expression level and FDP in UC. Full size im

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