BDH1 Antibody - #BF0318

(1)  
产品: BDH1 抗体
货号: BF0318
描述: Mouse monoclonal antibody to BDH1
应用: WB IHC ELISA
反应: Human, Mouse
分子量: 38kDa; 38kD(Calculated).
蛋白号: Q02338
RRID: AB_2833761

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 50ul RMB¥ 1800 现货
 100ul RMB¥ 2800 现货

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MSDS
说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Mouse
应用:
ELISA 1:10000, WB 1:500-1:2000, IHC 1:200-1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
克隆:
Monoclonal [AFB1737]
特异性:
BDH1 antibody detects endogenous levels of total BDH1.
RRID:
AB_2833761
引用格式: Affinity Biosciences Cat# BF0318, RRID:AB_2833761.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

3 hydroxybutyrate dehydrogenase (heart, mitochondrial); 3-hydroxybutyrate dehydrogenase; BDH; BDH_HUMAN; BDH1; D beta hydroxybutyrate dehydrogenase, mitochondrial; D-beta-hydroxybutyrate dehydrogenase; mitochondrial;

抗原和靶标

免疫原:

Purified recombinant fragment of human BDH1 expressed in E. Coli.

Uniprot:

Q02338(BDH_HUMAN) >>Visit HPA database.

基因/基因ID:
BDH1(622)
描述:
BDH1 (3-hydroxybutyrate dehydrogenase, type 1), it is a member of the short-chain dehydrogenase/reductase gene family. This protien forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. It catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism.
序列:
MLATRLSRPLSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMIYIR

研究背景

细胞定位:

Mitochondrion inner membrane. Mitochondrion matrix.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Homotetramer.

蛋白家族:

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

研究领域

· Metabolism > Lipid metabolism > Synthesis and degradation of ketone bodies.

· Metabolism > Carbohydrate metabolism > Butanoate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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