LYZL6 Antibody - #DF6212

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产品: LYZL6 抗体
货号: DF6212
描述: Rabbit polyclonal antibody to LYZL6
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
分子量: 17kDa; 17kD(Calculated).
蛋白号: O75951
RRID: AB_2838178

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 50ul RMB¥ 1250 现货
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
LYZL6 Antibody detects endogenous levels of total LYZL6.
RRID:
AB_2838178
引用格式: Affinity Biosciences Cat# DF6212, RRID:AB_2838178.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

EC 3.2.1.17; LYC1; Lysozyme homolog; Lysozyme like 6; UNQ754/PRO1485;

抗原和靶标

免疫原:
Uniprot:

O75951(LYZL6_HUMAN) >>Visit HPA database.

基因/基因ID:
LYZL6(57151)
表达:
O75951 LYZL6_HUMAN:

Expressed in testis, epididymis and spermatozoa (at protein level) (PubMed:16014814, PubMed:28182716). Expressed in late-stage spermatocytes and round spermatids (PubMed:28182716).

描述:
This gene encodes a member of the C-type lysozyme/alpha-lactalbumin family. C-type lysozymes are bacteriolytic factors that play a role in host defense, whereas alpha-lactalbumins mediate lactose biosynthesis. The encoded protein contains catalytic residues characteristic of C-type lysozymes and may play a role in male reproduction. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]
序列:
MTKALLIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNISKINENADGSFDYGLFQINSHYWCNDYKSYSENLCHVDCQDLLNPNLLAGIHCAKRIVSGARGMNNWVEWRLHCSGRPLFYWLTGCRLR

研究背景

功能:

May be involved sperm-egg plasma membrane adhesion and fusion during fertilization. Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus. Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH. Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6.

细胞定位:

Secreted. Cell surface. Cell projection>Cilium>Flagellum.
Note: Detected on the postacrosomal membrane of mature spermatozoa (PubMed:28182716).

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in testis, epididymis and spermatozoa (at protein level). Expressed in late-stage spermatocytes and round spermatids.

亚基结构:

Monomer.

蛋白家族:

Belongs to the glycosyl hydrolase 22 family.

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