CRHR1 Antibody - #AF5310

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产品: CRHR1 抗体
货号: AF5310
描述: Rabbit polyclonal antibody to CRHR1
应用: WB IHC IF/ICC
文献验证: WB, IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine
蛋白号: P34998
RRID: AB_2837795

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
CRHR1 Antibody detects endogenous levels of total CRHR1.
RRID:
AB_2837795
引用格式: Affinity Biosciences Cat# AF5310, RRID:AB_2837795.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Corticotropin releasing factor type 1 receptor; corticotropin releasing hormone receptor 1; Corticotropin-releasing factor receptor 1; Corticotropin-releasing hormone receptor 1; CRF R; crf receptor 1; crf receptor type 1; crf type 1; CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR; CRFR-1; CRFR1; CRFR1_HUMAN; CRH-R-1; CRH-R1; CRH-R1h; CRHR; Crhr1; CRHR1f; CRHR1L;

抗原和靶标

免疫原:

A synthesized peptide derived from human CRHR1, corresponding to a region within the internal amino acids.

基因/基因ID:
CRHR1(104909134)
描述:
This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Organismal Systems > Nervous system > Long-term depression.

文献引用

1). Environmental enrichment modulates HPA axis reprogramming in adult male rats exposed to early adolescent stress. Neuroscience research, 2021 (PubMed: 33901553) [IF=2.3]

Application: WB    Species: Rat    Sample: brain

Fig. 6. Protein expression of GR, MR, CRF1R and CRF2R in the hypothalamus and hippocampus.
2). Electroacupuncture in the treatment of IBS in rats: investigation of the mechanisms of CRH+ neurons in the paraventricular nucleus. Journal of neurophysiology, 2023 (PubMed: 37435647) [IF=2.1]

Application: IF/ICC    Species: Rat    Sample: brain

Figure 5. Electroacupuncture (EA) decreased the expression of corticotropin-releasing hormone receptor 1 (CRHR1) and corticotropin-releasing hormone receptor 2 (CRHR2) in the paraventricular nucleus (PVN) of experimental rats.

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