FSHR Antibody - #AF5242

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产品: FSHR 抗体
货号: AF5242
描述: Rabbit polyclonal antibody to FSHR
应用: WB IHC IF/ICC
文献验证: WB, IHC, IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit
蛋白ID: P23945
RRID: AB_2837728

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#AF5242-BP

FSHR Peptide

1mg
相关下载
抗原肽/阻断肽MS报告
抗原肽/阻断肽HPLC报告
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
FSHR Antibody detects endogenous levels of total FSHR.
RRID:
AB_2837728
引用格式: Affinity Biosciences Cat# AF5242, RRID:AB_2837728.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; Fshr; FSHR_HUMAN; FSHRO; LGR1; MGC141667; MGC141668; ODG1; ovarian dysgenesis 1;

抗原和靶标

免疫原:

A synthesized peptide derived from human FSHR, corresponding to a region within the internal amino acids.

基因/基因ID:
FSHR(2492)
描述:
Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

研究领域

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Organismal Systems > Endocrine system > Ovarian steroidogenesis.

文献引用

1). A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep. International journal of biological macromolecules, 2025 (PubMed: 39986531) [IF=7.7]
2). Di-(2-ethylhexyl) phthalate exposure induces ferroptosis by regulating the Nrf2-mediated signaling pathway in mouse ovaries. Ecotoxicology and environmental safety, 2024 (PubMed: 39321527) [IF=6.2]
3). CCDC134 enhances ovarian reserve function and angiogenesis by directly interacting with INHA in a mouse model of premature ovarian insufficiency. Apoptosis : an international journal on programmed cell death, 2025 (PubMed: 40042746) [IF=6.1]
4). DNA Methylation Mediates the Transcription of STAT4 to Regulate KISS1 During Follicular Development. Cells, 2025 (PubMed: 40214477) [IF=6.0]

Application: WB    Species: Mouse    Sample:

Figure 2. Effects of STAT4 on the function of GCs. The mRNA of cellular proliferation (A), cell cycle (B) and estrogen secretion-related genes (C) detected in GCs with STAT4 overexpression and knockdown. (D) The protein levels of STAR, P65, FSHR and CCNE1 in GCs with STAT4 overexpression and knockdown. The CCK-8 assay shows the viability of GCs with STAT4 overexpression (E) and knockdown (F). The EDU assay shows the proliferation of GCs with STAT4 overexpression (G) and knockdown (H). The measurements of cell cycle distributions in GCs with STAT4 overexpression (I) and knockdown (J). The measurements of E2 secretions in GCs with STAT4 overexpression (K) and knockdown (L). ns: not significant, *** p < 0.001, ** p < 0.01 and * p < 0.05.
5). Study on the effects and mechanisms of Wenzhong Bushen Formula in improving ovarian reserve decline in mice based on network pharmacology. Journal of ethnopharmacology, 2024 (PubMed: 38218503) [IF=4.8]
6). hUCMSCs restore ovarian function via angiopoietin 1/2 rebalance in POI rats. Journal of ovarian research, 2025 (PubMed: 41254793) [IF=4.0]

Application: IF/ICC    Species: human    Sample:

Fig. 5 Isolation and identification of rat ovarian microvascular endothelial cells (ROMECs). A Morphology of ROMECs (40×). B Viability of ROMECs after CTX treated. C Immunofluorescence staining of CD31, FSHR, Cyp17a1 (200×). DAPI is blue and stains the nucleus; CD31 positive is green; FSHR and Cyp17a1 positive are red. D Tube formation assay of ROMECs. Data were shown as mean ± SD of at least three independent experiments.
7). Transcriptomic analysis of theca cells in a PCOS rat model: insights into follicular development. Journal of ovarian research, 2025 (PubMed: 40544268) [IF=4.0]
8). Prenatal genistein exposure in rats affects pubertal onset and serum reproductive hormone levels in male offsprings via the hypothalamic-pituitary-gonadal axis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2025 (PubMed: 40320066) [IF=3.9]
9). Genome-wide association study of economic traits and functional characterization of MAN2A2 in the Jilin White Goose. Poultry science, 2026 (PubMed: 41389538) [IF=3.8]
10). IFI6 regulation of physiological functions in granulosa cells. CELLULAR SIGNALLING, 2025 [IF=3.7]
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