CDH13 Antibody - #AF5203

Figure 1. T-cadherin expression detected in lung tissues of healthy controls and COVID-19 patients. (A) Representative sections of parenchymal lung tissue from a healthy control and a COVID-19 patient stained for T-cadherin as revealed with DAB HRP Substrate (brown) and counterstained with hematoxylin. Scale bar 100 μm. (B) Representative sections of the hilar region of the lung tissue from a healthy control and a COVID-19 patient stained for T-cadherin as revealed with DAB HRP Substrate (brown). Arrows point to T-cadherin expression. Scale bar 100 μm. (C–G) T-cadherin staining scores in the images of lung tissue sections of COVID-19 patients and control healthy donors in the tissue as a whole, (C), stroma (D), bronchioles (E), large (F) and small blood vessels (G). Images were analyzed by the Positive Pixel Count V9 algorithm of ImageScope (Aperio), which counts pixels of the predetermined color (brown for T-cadherin, positive pixels) and pixels related to other colors (negative pixels). A staining score was calculated as the number of positive pixels/(number of positive + negative pixels). Data are shown as individual values, median and interquartile range, ns - non-significant, *p < 0.05, **p < 0.01, Mann-Whitney test.