S100A10 Antibody - #AF5180

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产品: S100A10 抗体
货号: AF5180
描述: Rabbit polyclonal antibody to S100A10
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: P60903
RRID: AB_2837666

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
S100A10 Antibody detects endogenous levels of total S100A10.
RRID:
AB_2837666
引用格式: Affinity Biosciences Cat# AF5180, RRID:AB_2837666.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

42C; AA409961; AL024248; Annexin II ligand; Annexin II ligand, calpactin I, light polypeptide; Annexin II tetramer (AIIt) p11 subunit; Annexin II, light chain; ANX2L; ANX2LG; Ca[1]; CAL12; CAL1L; Calpactin I light chain; Calpactin I, p11 subunit; Calpactin-1 light chain; Cellular ligand of annexin II; CLP11; GP11; MGC111133; Nerve growth factor-induced protein 42C; OTTHUMP00000015269; OTTHUMP00000015270; p10; p10 protein; p11; Protein S100 A10; Protein S100-A10; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium binding protein A10 (calpactin); S100 calcium binding protein A10; S100 calcium-binding protein A10; S100a10; S10AA_HUMAN;

抗原和靶标

免疫原:

A synthesized peptide derived from human S100A10, corresponding to a region within the internal amino acids.

基因/基因ID:
S100A10(6281)
描述:
Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

文献引用

1). Notch signaling activation contributes to paclitaxel-induced neuropathic pain via activation of A1 astrocytes. European journal of pharmacology, 2022 (PubMed: 35777441) [IF=4.2]

Application: WB    Species: Rat    Sample: spinal cord

Fig. 2. Astrocytes were activated as the A1 phenotype in spinal cord. (A–E) The spinal expression of GFAP, C3 and Serping1 were significantly increased in spinal cord at 14 d and 21 d after intraperitoneal injection of paclitaxel, while the spinal S100A10 and PTX3 were decreased at 14 d and 21 d (*p < 0.05, **p < 0.01, ***p < 0.001 compared with the vehicle group, n=6 in each group). (F–G) Dual-label immunofluorescence showed that A1 astrocytes markers (C3, Serping1) and A2 astrocytes markers (S100A10, PTX3) were mostly colocalized with GFAP in the dorsal horn of spinal cord. Scale Bar: 50 μm and 100 μm, respectively (n=4). The white arrow indicated typical co-staining cells.

Application: IF/ICC    Species: Rat    Sample: spinal cord

Fig. 2. Astrocytes were activated as the A1 phenotype in spinal cord. (A–E) The spinal expression of GFAP, C3 and Serping1 were significantly increased in spinal cord at 14 d and 21 d after intraperitoneal injection of paclitaxel, while the spinal S100A10 and PTX3 were decreased at 14 d and 21 d (*p < 0.05, **p < 0.01, ***p < 0.001 compared with the vehicle group, n=6 in each group). (F–G) Dual-label immunofluorescence showed that A1 astrocytes markers (C3, Serping1) and A2 astrocytes markers (S100A10, PTX3) were mostly colocalized with GFAP in the dorsal horn of spinal cord. Scale Bar: 50 μm and 100 μm, respectively (n=4). The white arrow indicated typical co-staining cells.

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