P2RY8 Antibody - #DF5137

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产品: P2RY8 抗体
货号: DF5137
描述: Rabbit polyclonal antibody to P2RY8
应用: WB IF/ICC
反应: Human
预测: Rabbit
分子量: 41 KD; 41kD(Calculated).
蛋白号: Q86VZ1
RRID: AB_2837496

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MS Report
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Rabbit(83%)
克隆:
Polyclonal
特异性:
P2RY8 Antibody detects endogenous levels of total P2RY8.
RRID:
AB_2837496
引用格式: Affinity Biosciences Cat# DF5137, RRID:AB_2837496.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

P2RY8; P2RY8_HUMAN; P2Y purinoceptor 8; P2Y8; Purinergic receptor P2Y G protein coupled 8;

抗原和靶标

免疫原:
Uniprot:

Q86VZ1(P2RY8_HUMAN) >>Visit HPA database.

基因/基因ID:
P2RY8(286530)
表达:
Q86VZ1 P2RY8_HUMAN:

Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.

序列:
MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQESVF

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
83
Pig
0
Horse
0
Bovine
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q86VZ1 作为底物

Site PTM Type Enzyme
N5 N-Glycosylation
S6 Phosphorylation
N11 N-Glycosylation
T13 Phosphorylation
Y127 Phosphorylation
S130 Phosphorylation
K132 Ubiquitination
Y139 Phosphorylation
S263 Phosphorylation
Y272 Phosphorylation
T320 Phosphorylation
S324 Phosphorylation
S327 Phosphorylation
T331 Phosphorylation
S332 Phosphorylation
S335 Phosphorylation
S357 Phosphorylation

研究背景

功能:

Probable receptor for purines coupled to G-proteins.

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.

蛋白家族:

Belongs to the G-protein coupled receptor 1 family.

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

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