OR10A6 Antibody - #DF5047

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产品: OR10A6 抗体
货号: DF5047
描述: Rabbit polyclonal antibody to OR10A6
应用: WB IF/ICC
反应: Human
预测: Dog
分子量: 35 KD; 35kD(Calculated).
蛋白号: Q8NH74
RRID: AB_2837406

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 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Dog(89%)
克隆:
Polyclonal
特异性:
OR10A6 Antibody detects endogenous levels of total OR10A6.
RRID:
AB_2837406
引用格式: Affinity Biosciences Cat# DF5047, RRID:AB_2837406.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

O10A6_HUMAN; Olfactory receptor family 10 subfamily A member 6; Olfactory receptor 10A6; Olfactory receptor OR11-96; OR10A6; OR11 96;

抗原和靶标

免疫原:
Uniprot:

Q8NH74(O10A6_HUMAN) >>Visit HPA database.

基因/基因ID:
OR10A6(390093)
序列:
MERQNQSCVVEFILLGFSNYPELQGQLFVAFLVIYLVTLIGNAIIIVIVSLDQSLHVPMYLFLLNLSVVDLSFSAVIMPEMLVVLSTEKTTISFGGCFAQMYFILLFGGAECFLLGAMAYDRFAAICHPLNYQMIMNKGVFMKLIIFSWALGFMLGTVQTSWVSSFPFCGLNEINHISCETPAVLELACADTFLFEIYAFTGTFLIILVPFLLILLSYIRVLFAILKMPSTTGRQKAFSTCAAHLTSVTLFYGTASMTYLQPKSGYSPETKKVMSLSYSLLTPLLNLLIYSLRNSEMKRALMKLWRRRVVLHTI

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Dog
89
Bovine
78
Pig
0
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

Odorant receptor.

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Belongs to the G-protein coupled receptor 1 family.

研究领域

· Organismal Systems > Sensory system > Olfactory transduction.

文献引用

1). Distinct sets of olfactory receptors highly expressed in different human tissues evaluated by meta-transcriptome analysis: Association of OR10A6 in skin with keratinization. Frontiers in Cell and Developmental Biology (PubMed: 36776557) [IF=5.5]

Application: IF/ICC    Species: Human    Sample: skin

FIGURE 3 Expression of ORs in human keratinocytes and skin. (A) RT-PCR analysis of OR5P2, OR5P3, and OR10A6. GAPDH was used for RNA quality control. M: Marker. (B) Immunofluorescence staining of OR10A6 (green) in human keratinocytes and skin. Cell nuclei appear in blue or white. Magnified sections are indicated by white dashed squares. Bar = 50 μm. (C–F) Immunofluorescence staining of OR10A6 (green) and KRT14, Melan A, Ki-67 or MCSP (red) in human skin. Cell nuclei appear in white. Magnified sections are shown in white dashed squares. Bar = 20 μm. (G) Ratio of OR10A6-positive cells, OR10A6 + Ki-67-positive cells and OR10A6 + MCSP-positive cells counted in skin sections.

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