MERTK Antibody - #DF4785

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产品: MERTK 抗体
货号: DF4785
描述: Rabbit polyclonal antibody to MERTK
应用: WB IF/ICC
文献验证: WB, IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
蛋白号: Q12866
RRID: AB_2837139

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
MERTK Antibody detects endogenous levels of total MERTK.
RRID:
AB_2837139
引用格式: Affinity Biosciences Cat# DF4785, RRID:AB_2837139.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

c MER; c mer proto oncogene tyrosine kinase; c-mer; cMER; cmer protooncogene tyrosine kinase; Eyk; MER; MER receptor tyrosine kinase; MERK; MERPEN; Mertk; MERTK c-mer proto-oncogene tyrosine kinase; MERTK_HUMAN; MGC133349; nmf12; Nyk; Proto oncogene tyrosine protein kinase MER; Proto oncogene tyrosine protein kinase MER precursor; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; RP38; STK kinase; Tyrosine-protein kinase Mer;

抗原和靶标

免疫原:

A synthesized peptide derived from human MERTK, corresponding to a region within the internal amino acids.

基因/基因ID:
MERTK(10461)

文献引用

1). Screen of FDA-approved drug library identifies vitamin K as anti-ferroptotic drug for osteoarthritis therapy through Gas6. Journal of Pharmaceutical Analysis, 2025 [IF=6.1]
2). Study on the involvement of microglial S100A8 in neuroinflammation and microglia activation during migraine attacks. Molecular and cellular neurosciences, 2024 (PubMed: 39111720) [IF=2.6]

Application: WB    Species: Rat    Sample:

Fig. 2. Validation the expression of DEGs related to microglia in the trigeminal ganglion (TG), and medulla oblongata (MO) and microglia of migraine rats. The mRNA levels (A) and protein expression (B) of MAFB, MERTK, SLCO2B1, S100A9, and S100A8 in the TG. The mRNA levels (C) and protein expression of MAFB, MERTK, SLCO2B1, S100A9, and S100A8 in the MO (D). ⁎P < 0.05, ⁎⁎P < 0.01, ⁎⁎⁎P < 0.001 vs. Control.
3). Protective Role of MerTK in Diabetic Peripheral Neuropathy via Inhibition of the NF-κB Signaling Pathway. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2024 (PubMed: 38588709)

Application: IF/ICC    Species: Rat    Sample:

Fig. 2 Immunofluorescence detection of MerTK expression in each group. Confocal images of MerTK (green) and DAPI (blue) staining of the nucleus. Scale bar=500 μm (first column). Scale bar=50 μm (columns 2, 3, and 4). Rat counts per group were: CON: 14, CON+MRX-2843: 14, T2DM: 10, DPN: 12, DPN+MRX-2843: 10, with a uniform age of 96 weeks. Sciatic nerves served as the study tissue. MerTK, mer tyrosine kinase; CON, control group; MRX, MerTK-specific inhibitor; T2DM, type 2 diabetes mellitus; DPN, diabetic peripheral neuropathy.|

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