产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4777, RRID:AB_2837131.
展开/折叠
DAP kinase related apoptosis inducing protein; DAP kinase related apoptosis inducing protein kinase 2; DAP kinase-related apoptosis-inducing protein kinase 2; Death associated protein kinase related 2; DRAK 2; DRAK2; Serine/threonine kinase 17b; Serine/threonine kinase 17b apoptosis inducing; Serine/threonine protein kinase 17B; Serine/threonine-protein kinase 17B; ST17B_HUMAN; STK 17B; Stk17b;
抗原和靶标
Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
- O94768 ST17B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSLPNPHELVSDLLC
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.
Autophosphorylated.
Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment.
Note: Colocalizes with STK17B at the plasma membrane.
Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
Interacts with CHP1; the interaction induces CHP1 to translocate from the Golgi to the nucleus.
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
限制条款
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