产品: ARX 抗体
货号: DF4674
描述: Rabbit polyclonal antibody to ARX
应用: WB IF/ICC
文献验证: WB, IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Sheep, Rabbit, Dog
蛋白号: Q96QS3
RRID: AB_2837025

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 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
ARX Antibody detects endogenous levels of total ARX.
RRID:
AB_2837025
引用格式: Affinity Biosciences Cat# DF4674, RRID:AB_2837025.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Aristaless related homeobox gene; Aristaless-related homeobox; Arx; ARX_HUMAN; Homeobox protein ARX; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRXS1; phox2a; PRTS;

抗原和靶标

免疫原:

A synthesized peptide derived from human ARX, corresponding to a region within the internal amino acids.

基因/基因ID:

文献引用

1). In utero exposure to phenanthrene induced islet cell dysfunction in adult mice: sex differences in the effects and potential causes. Science of The Total Environment, 2021 (PubMed: 33513515) [IF=8.2]

Application: WB    Species: mice    Sample: islet cell

Fig. 4. The expression of pancreatic proteins that participate in islet cell function of adult F1 mice. The data were shown as the mean ± SE and analyzed with SPSS 19.0 software. Significant difference (p < 0.05) was tested using one-way ANOVA (Duncan's test), which are labeled by *. n = 4, 3 dams from each group, and 1–2 F1 mice from each dam.

2). Exposure to Aroclor 1254 differentially affects the survival of pancreatic β-cells and α-cells in the male mice and the potential reason. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020 (PubMed: 31706244) [IF=6.2]

Application: IF/ICC    Species: mouse    Sample: islet cell

Fig. 6.| Immunofluorescence analysis of Pdx1 and Arx expression in islet cells of male mice exposed to Aroclor 1254 for 60 days. (A) Representative images of triple staining for insulin (green), Pdx-1 (red), and DAPI (blue) on fixed, paraffin-embedded pancreas sections. (B) Percentage of Pdx-1 positive data are presented as mean ± SE (n = 3). (C) Representative images of triple staining for glucagon (green), Arx (red), and DAPI (blue) on fixed, paraffin-embedded pancreas sections. (D)Percentage of Arx positive data are presented as mean ± SE (n = 3). Means of exposures not sharing a common letter are significantly different at P < 0.05 as assessed by one-way ANOVA followed by the Duncan test. Scale bar = 50 μm.

3). The effects of EGCG supplementation on pancreatic islet α and β cells distribution in adult male mice. The Journal of nutritional biochemistry, 2024 (PubMed: 37951555) [IF=4.8]

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