TAZ Antibody - #DF4653

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产品: TAZ 抗体
货号: DF4653
描述: Rabbit polyclonal antibody to TAZ
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
蛋白号: Q16635
RRID: AB_2837004

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
TAZ Antibody detects endogenous levels of total TAZ.
RRID:
AB_2837004
引用格式: Affinity Biosciences Cat# DF4653, RRID:AB_2837004.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Barth syndrome; Cardiomyopathy dilated 3A (X linked); EFE2; Endocardial fibroelastosis 2; Protein G4.5; Tafazzin; TAZ; TAZ protein; TAZ_HUMAN;

抗原和靶标

免疫原:

A synthesized peptide derived from human TAZ, corresponding to a region within the internal amino acids.

基因/基因ID:
TAZ(6901)

研究领域

· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.

文献引用

1). An H2 S-BMP6 Dual-Loading System with Regulating Yap/Taz and Jun Pathway for Synergistic Critical Limb Ischemia Salvaging Therapy. Advanced healthcare materials, 2023 (PubMed: 37531238) [IF=10.0]
2). Wuweixiaoduyin regulates TAZ-mediated immunoregulatory properties of Treg/TH17 cells in chronic osteomyelitis. Biotechnology & genetic engineering reviews, 2023 (PubMed: 36641597) [IF=6.5]
3). YAP signaling in horizontal basal cells promotes the regeneration of olfactory epithelium after injury. Stem cell reports, 2022 (PubMed: 35148842) [IF=5.9]

Application: WB    Species: Mouse    Sample:

Figure 1 YAP is upregulated and activated in HBCs after acute OE injury (A–D) Double immunostaining of YAP (green) and p63 (red) (A), YAP (green) and LSD1 (red) (B), YAP (green) and GAP43 (red) (C), and YAP (green) and OMP (red) (D) in the OE of 2-month-old C57BL/6 mice. (E) Western blot detected the expression of p-YAP and YAP in the OE of 2-month-old C57BL/6 mice at 0, 3, 5, 7, and 14 dpl. (F and G) Quantitative analysis of the relative p-YAP/YAP (F) and YAP (G) levels as shown in (E) (n = 8 blots from 4 mice per group, normalized to the 0 dpl group). (H) Western blot detected the expression of TAZ in the OE of 2-month-old C57BL/6 mice at 0, 3, 5, 7, and 14 dpl. (I) Quantitative analysis of the relative TAZ level as shown in (H) (n = 15 blots from 5 mice per group, normalized to the 0 dpl group). (J) Immunohistochemistry detected the expression of YAP in the OE of 2-month-old C57BL/6 mice at 0, 3, 7, and 14 dpl. (K) Quantitative analysis of the relative YAP density as shown in (J) (n = 10 sections from 5 mice per group). (L) Double immunostaining of YAP (green) and p63 (red) in the OE of 2-month-old C57BL/6 mice at 0, 2, 5, and 14 dpl. (M) Quantitative analysis of the percentage of both YAP+ and p63+ cells over p63+ cells as shown in (L) (n = 9 sections from 3 mice per group). Images of selected regions are shown at higher magnification. Data are mean ± SEM, one-way ANOVA with Bonferroni’s post tests, compared with 0 dpl group; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Scale bars, 20 μm.
4). TAZ Induces Migration of Microglia and Promotes Neurological Recovery After Spinal Cord Injury. Frontiers in pharmacology, 2022 (PubMed: 35833021) [IF=5.6]

Application: WB    Species: Mouse    Sample: spinal cords

FIGURE 1. TAZ was significantly increased and localized in microglia. (A) Western blot analysis of TAZ expression in spinal cords at 3d, 7d, 14d, and 28d after SCI, compared with Pre (pre-operation, Pre). (B) Quantitative analysis of TAZ level as shown in (A). The blots (n = 3 per group) were quantified by a densitometric method using ImageJ software. GAPDH was used as the loading control. Data were mean ± SEM. *p
5). Protecting mitochondria via inhibiting VDAC1 oligomerization alleviates ferroptosis in acetaminophen-induced acute liver injury. Cell biology and toxicology, 2022 (PubMed: 34401974) [IF=5.3]
6). Manganese drives ferroptosis of cancer cells via YAP/TAZ phase separation activated ACSL4 in OSCC. Oral diseases, 2024 (PubMed: 38462885) [IF=2.9]
7). Gallic acid from Terminalia chebula inhibited the growth of esophageal carcinoma cells by suppressing the Hippo signal pathway. Iranian Journal of Basic Medical Sciences, 2020 (PubMed: 33235697) [IF=2.1]

Application: WB    Species: human    Sample: EC9706 and KYSE450 cells

Figure 6. Effect of different concentrations (10, 20, and 40 μg/ml) of GA on the Hippo signal pathway in EC9706 and KYSE450 cells by Western blotting assay

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