UBAC1 Antibody - #DF4598

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产品: UBAC1 抗体
货号: DF4598
描述: Rabbit polyclonal antibody to UBAC1
应用: WB IF/ICC
反应: Human
预测: Zebrafish, Horse, Dog, Chicken, Xenopus
分子量: 45 KD; 45kD(Calculated).
蛋白号: Q9BSL1
RRID: AB_2836962

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
MSDS
说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Zebrafish(80%), Horse(%), Dog(%), Chicken(%), Xenopus(%)
克隆:
Polyclonal
特异性:
UBAC1 Antibody detects endogenous levels of total UBAC1.
RRID:
AB_2836962
引用格式: Affinity Biosciences Cat# DF4598, RRID:AB_2836962.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

1110033G07Rik; AA407978; E3 ubiquitin-protein ligase subunit KPC2; GBDR1; Glialblastoma cell differentiation-related protein 1; Glialblastoma differentiation-related protein 1; Kip1 ubiquitination-promoting complex protein 2; kpc 2; Kpc2; OTTHUMP00000022563; Putative glialblastoma cell differentiation-related protein; RP11-432J22.3; UBA domain containing 1; UBA domain-containing protein 1; UBAC 1; UBAC1; Ubadc1; Ubiquitin associated domain containing 1; Ubiquitin-associated domain-containing protein 1;

抗原和靶标

免疫原:
Uniprot:

Q9BSL1(UBAC1_HUMAN) >>Visit HPA database.

基因/基因ID:
UBAC1(10422)
表达:
Q9BSL1 UBAC1_HUMAN:

Ubiquitous.

序列:
MFVQEEKIFAGKVLRLHICASDGAEWLEEATEDTSVEKLKERCLKHCAHGSLEDPKSITHHKLIHAASERVLSDARTILEENIQDQDVLLLIKKRAPSPLPKMADVSAEEKKKQDQKAPDKEAILRATANLPSYNMDRAAVQTNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAEDPTIDTPLPGQAPPEAEGATAAASEAAAGASATDEEARDELTEIFKKIRRKREFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDKGIDPDSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Xenopus
90
Horse
80
Dog
80
Zebrafish
80
Chicken
80
Pig
70
Bovine
70
Sheep
60
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous.

亚基结构:

Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain.

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