CCT6A Antibody - #DF4562

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产品: CCT6A 抗体
货号: DF4562
描述: Rabbit polyclonal antibody to CCT6A
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Bovine, Sheep, Dog, Chicken
蛋白号: P40227
RRID: AB_2836913

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
CCT6A Antibody detects endogenous levels of total CCT6A.
RRID:
AB_2836913
引用格式: Affinity Biosciences Cat# DF4562, RRID:AB_2836913.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Acute morphine dependence related protein 2; Amino acid transport defect complementing; CCT zeta 1; CCT zeta; CCT-zeta; CCT-zeta-1; CCT6; CCTZ; Chaperonin containing T complex subunit 6; Chaperonin containing TCP1 subunit 6A; Chaperonin containing TCP1 subunit 6A (zeta 1); Histidine transport regulator 3; HTR3; MGC126214; MGC126215; MoDP 2; MoDP-2; MoDP2; T complex protein 1 subunit zeta; T complex protein 1 zeta subunit; TCP 1 zeta; TCP-1-zeta; TCP1 zeta; TCP20; TCPZ; TTCP20;

抗原和靶标

免疫原:

A synthesized peptide derived from human CCT6A, corresponding to a region within the internal amino acids.

基因/基因ID:
CCT6A(908)

文献引用

1). CCT6A alleviates pulmonary fibrosis by inhibiting HIF-1α-mediated lactate production. Journal of molecular cell biology, 2024 (PubMed: 38760881) [IF=5.3]

Application: WB    Species: Mouse    Sample:

Figure 1CCT6A is highly expressed in lung tissues of IPF and BLM-induced lung fibrosis in mice. (A) Publicly available array data (GSE47460) showing CCT6A expression levels in lung tissues of IPF (n = 160) and control subjects (n = 108). (B) Correlation between CCT6A expression level and the diffusion capacity for carbon monoxide, determined by Pearson Correlation. (C) Representative images of immunohistochemical analysis of CCT6A level in human lung tissue samples (n = 4). Boxed regions are magnified from the panel. Scale bar, 50 μm. (D) Immunoblot analysis of Cct6a, α-SMA, and Col1a1 levels in lung tissues of BLM-induced lung fibrosis (n = 3) and control group (n = 3). (E) Representative images of immunohistochemistry analysis of Cct6a level in mouse lung tissue samples (n = 4). Boxed regions are magnified from the panel. Scale bar, 50 μm. (F) Representative images of co-immunostaining of Cct6a and SPC (an AT2 marker) in mouse lung tissue samples (n = 5). Scale bar, 50 μm. ***P < 0.001, ****P 

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