SLC6A3 Antibody - #DF4529

>>奖励金 进行中>>
>>买2送1 进行中>>
(8)   (5)   一键复制产品
产品: SLC6A3 抗体
货号: DF4529
描述: Rabbit polyclonal antibody to SLC6A3
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Dog
蛋白ID: Q01959
RRID: AB_2836880

浏览相似产品>>

   规格 价格 库存
 50ul RMB¥ 1100 1250 现货
 100ul RMB¥ 2100 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
对照产品

#DF4529-BP

SLC6A3 Peptide

1mg
相关下载
抗原肽/阻断肽MS报告
抗原肽/阻断肽HPLC报告
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
SLC6A3 Antibody detects endogenous levels of total SLC6A3.
RRID:
AB_2836880
引用格式: Affinity Biosciences Cat# DF4529, RRID:AB_2836880.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

DA transporter; DAT 1; DAT; DAT1; Dopamine transporter 1; Dopamine transporter; PKDYS; SC6A3_HUMAN; SLC6A3; Sodium dependent dopamine transporter; Sodium-dependent dopamine transporter; Solute carrier family 6 (neurotransmitter transporter dopamine), member 3; Solute carrier family 6 (neurotransmitter transporter), member 3; Solute carrier family 6 member 3; Variable number tandem repeat (VNTR);

抗原和靶标

免疫原:

A synthesized peptide derived from human SLC6A3, corresponding to a region within the internal amino acids.

基因/基因ID:
SLC6A3(6531)

研究领域

· Human Diseases > Neurodegenerative diseases > Parkinson's disease.

· Human Diseases > Substance dependence > Cocaine addiction.

· Human Diseases > Substance dependence > Amphetamine addiction.

· Human Diseases > Substance dependence > Alcoholism.

· Organismal Systems > Nervous system > Dopaminergic synapse.

文献引用

1). Lactobacillus reuteri-derived γ-amino butyric acid alleviates MPTP-induced Parkinson's disease through inhibiting ferroptosis via the AKT-GSK3β-GPX4 axis. NPJ Parkinson's disease, 2025 (PubMed: 40467635) [IF=8.7]
2). Blue honeysuckle (Lonicera caerulea L.)-anthocyanins and cyanidin-3-O-glucoside protect dopaminergic neurons against ferroptosis by activating the Nrf2-GPX7 axis. Free radical biology & medicine, 2025 (PubMed: 40738179) [IF=7.1]
3). Integrative multilevel exploration of the mechanism by which Er-Zhi-Wan alleviates the Parkinson's disease (PD)-like phenotype in the MPTP-induced PD mouse model. Biomedicine & Pharmacotherapy, 2023 (PubMed: 37348406) [IF=6.9]

Application: WB    Species: Mouse    Sample:

Fig. 3. EZW reduces the dopaminergic neuron damage in MPTP-PD mice. (A) The expression of TH, α-syn, and DAT in the striatum of each group was measured by Western blot analysis (n = 3 per group). (B) Relative densities of TH, α-syn, DAT, and β-actin were measured in different groups using densitometric analysis of Western blots. TH, α-syn, and DAT proteins were normalized to β-actin, and were expressed as the fold difference relative to the control group (Data represent the mean ± SD, n = 3. * P 
4). Long-life triclosan exposure induces ADHD-like behavior in rats via prefrontal cortex dopaminergic deficiency. Ecotoxicology and environmental safety, 2024 (PubMed: 39047361) [IF=6.2]

Application: WB    Species: rat    Sample:

Fig. 3. The effect of TCS on dopaminergic associated mRNA and proteins in vivo. (A) The DA levels in PFC of long-life TCS exposed model rats. (B) Illustration of protein bands of TH, DDC, VMAT2, DRD1, DRD2 and DAT. (C) The relative mRNA and protein expression levels of TH. (D) The relative mRNA and protein expression levels of DDC. (E) The relative mRNA and protein expression levels of VMAT2. (F) The relative mRNA and protein expression levels of DRD1. (G) The relative mRNA and protein expression levels of DRD2. (H) The relative mRNA and protein expression levels of DAT. n = 6.
5). Neuroprotective Effect of Abscisic Acid on MPTP-Induced Parkinson's Disease in Mice. Molecular nutrition & food research, 2025 (PubMed: 40357876) [IF=4.5]
6). RND3 modulates microglial polarization and alleviates neuroinflammation in Parkinson's disease by suppressing NLRP3 inflammasome activation. Experimental cell research, 2024 (PubMed: 38744409) [IF=3.3]
7). Activation of mitophagy via miR-223/NLRP3 axis ameliorates dopaminergic neuronal damage in parkinson's disease. Metabolic brain disease, 2026 (PubMed: 41870730) [IF=3.2]
8). The protective effects of repetitive transcranial magnetic stimulation with different high frequencies on motor functions in MPTP/probenecid induced Parkinsonism mouse models. Brain and behavior, 2024 (PubMed: 38956819) [IF=2.6]

Application: WB    Species: Mouse    Sample:

FIGURE 6 Effects of repetitive transcranial magnetic stimulation (rTMS) with different high frequencies on DA transporter proteins (DAT and VMAT-2) in striata. Representative images of DAT (a) and VMAT-2 (c) western blot in the striata were shown. The averaged data of DAT (b) and VMAT-2 (d) proteins in groups were displayed. Values are expressed as the mean ± SEM. *p < .05, **p < .01, ****p < .0001. I: Control group; II: MPTP/p group; III: MPTP/p + 5 Hz group; IV: MPTP/p + 10 Hz group; V: MPTP/p + 15 Hz group; VI: MPTP/p + 20 Hz group; VII: MPTP/p + iTBS group. B: F(6,14) = 5.937, D: F(6,14) = 13.880.

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.