SLC28A2 Antibody - #DF4522

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产品: SLC28A2 抗体
货号: DF4522
描述: Rabbit polyclonal antibody to SLC28A2
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Horse, Sheep, Rabbit
蛋白号: O43868
RRID: AB_2836873

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
SLC28A2 Antibody detects endogenous levels of total SLC28A2.
RRID:
AB_2836873
引用格式: Affinity Biosciences Cat# DF4522, RRID:AB_2836873.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CNT 2; CNT2; Concentrative nucleoside transporter 2; FLJ21468; hCNT2; HsT17153; MGC138252; Na(+)/nucleoside cotransporter 2; S28A2_HUMAN; Slc28a2; Sodium coupled nucleoside transporter 2; Sodium-coupled nucleoside transporter 2; Sodium/nucleoside cotransporter 2; Sodium/purine nucleoside co transporter; Sodium/purine nucleoside co-transporter; Solute carrier family 28 (sodium coupled nucleoside transporter) member 2; Solute carrier family 28 member 2; SPNT; SPNT1;

抗原和靶标

免疫原:

A synthesized peptide derived from human SLC28A2, corresponding to a region within the internal amino acids.

基因/基因ID:
SLC28A2(9153)

文献引用

1). Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model. NPJ biofilms and microbiomes, 2024 (PubMed: 38509085) [IF=9.2]
2). 5-O-Methylvisammioside, a novel inhibitor of CNT2, improves hyperuricemia by inhibiting intestinal purine nucleoside absorption with a safe profile.. BIOCHEMICAL PHARMACOLOGY, 2025 [IF=5.6]

Application: WB    Species: Mouse    Sample:

Fig. 1. Effects of a high UA environment on CNT2. (A) The cell viability was assayed by stimulating HIEC with different concentrations of UA for 24 h (n = 6). (B-C) Relative mRNA and protein levels of CNT2 were determined by qPCR (n = 6) and WB (n = 3). (D-E) CNT2 expression was detected using confocal microscopy. Red fluorescence intensity represents the amount of CNT2 (scale bar = 50 μm; n = 6). (F) Body weight and sUA of HUA mice modeled for 4 weeks (n = 6). (G,I) IHC staining and positive staining intensity analysis of CNT2. (scale bar = 100 μm; n = 6). (H) H&E staining images of the duodenum, jejunum, and ileum (scale bar = 100 μm; n = 6). *p < 0.05, **p < 0.01, and ***p < 0.001, compared to 0 μM or CON.
3). e5NT inhibitor protects acute restraint stress‐induced depression by regulating nucleoside release in mice. JOURNAL OF PHARMACY AND PHARMACOLOGY, 2020 (PubMed: 32743802) [IF=2.8]

Application: WB    Species: mouse    Sample: hippocampus

Figure 2 |Effects of the expression changes in the expression of nucleoside-metabolizing enzyme induced by ARS in the hippocampus of mice.There were no significant changes in the expression of CNT1, CNT2 (a), ENT1 and ENT2 (b).

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