产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4503, RRID:AB_2836854.
展开/折叠
Endophilin B2; Endophilin-B2; OTTHUMP00000022320; PP6569; PP9455; Retinoid receptor induced gene 1; RRIG1; SH3 containing protein SH3GLB2; SH3 domain GRB2 like endophilin B2; SH3 domain-containing GRB2-like protein B2; SH3GLB2; SHLB2_HUMAN;
抗原和靶标
- Q9NR46 SHLB2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9NR46 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K6 | Methylation | Uniprot | |
| K7 | Methylation | Uniprot | |
| K7 | Ubiquitination | Uniprot | |
| S10 | Phosphorylation | Uniprot | |
| K26 | Ubiquitination | Uniprot | |
| K32 | Ubiquitination | Uniprot | |
| K50 | Ubiquitination | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| Y77 | Phosphorylation | Uniprot | |
| K79 | Ubiquitination | Uniprot | |
| T108 | Phosphorylation | Uniprot | |
| T109 | Phosphorylation | Uniprot | |
| K117 | Ubiquitination | Uniprot | |
| K123 | Ubiquitination | Uniprot | |
| T142 | Phosphorylation | Uniprot | |
| K153 | Ubiquitination | Uniprot | |
| K173 | Ubiquitination | Uniprot | |
| K178 | Acetylation | Uniprot | |
| K180 | Acetylation | Uniprot | |
| K185 | Acetylation | Uniprot | |
| K185 | Ubiquitination | Uniprot | |
| T188 | Phosphorylation | Uniprot | |
| T195 | Phosphorylation | Uniprot | |
| R198 | Methylation | Uniprot | |
| S205 | Phosphorylation | Uniprot | |
| S207 | Phosphorylation | Uniprot | |
| R230 | Methylation | Uniprot | |
| S259 | Phosphorylation | Uniprot | |
| T262 | Phosphorylation | Uniprot | |
| Y263 | Phosphorylation | Uniprot | |
| K276 | Ubiquitination | Uniprot | |
| S395 | Phosphorylation | Uniprot |
研究背景
Cytoplasm.
Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.
Homodimer, and heterodimer with SH3GLB1.
Belongs to the endophilin family.
研究领域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
限制条款
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